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CXCR2 antibody (AA 316-360)

Name: CXCR2 antibody (AA 316-360)
SKU: ABIN732218
Price: 384.62 USD
Availability: InStock

CXCR2 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated

Mouse bone lysates probed with Rabbit Anti-CXCR2/CD182 Polyclonal Antibody, Unconjugated at 1:500 for 90 min at 37˚C.

Formalin-fixed and paraffin embedded rat hepatoma labeled with Anti-CXCR2/CD182 Polyclonal Antibody, Unconjugated (ABIN732218) followed by conjugation to the secondary antibody and DAB staining

IHC

Formalin-fixed and paraffin embedded human rectal carcinoma labeled with Anti-CXCR2/CD182 Polyclonal Antibody, Unconjugated (ABIN732218) at 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC

Characterization of MIF receptors by confocal microscopy.

IF (cc)

4 images

(5 references)

Catalog No. ABIN732218

Datasheet as PDF

Target See all CXCR2 Antibodies

CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
Binding Specificity
14

14

12

6

5

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 316-360
Reactivity
78

38

23

2

2

1

1

1
Human, Mouse, Rat
Host
71

10

1

1
Rabbit
Compatible Secondaries
Clonality
73

9

1
Polyclonal
Conjugate
46

6

5

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
This CXCR2 antibody is un-conjugated
Application
50

30

22

18

16

14

13

10

6

3

2

2

2

1

1
Western Blotting (WB), ELISA

Cross-Reactivity

Human, Mouse, Rat

Predicted Reactivity

Dog,Cow,Pig,Horse,Rabbit,Guinea Pig

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human CXCR2

Isotype

IgG
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (pSer347) antibody
CXCR2 Reactivity: Human, Mouse WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) antibody
CXCR2 Reactivity: Human WB, ELISA, IHC, FACS, ICC, Neut Host: Mouse Monoclonal 7E9H12 unconjugated

anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (AA 1-40) antibody
CXCR2 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (N-Term) antibody
CXCR2 Reactivity: Human WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (AA 1-57) antibody
CXCR2 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (C-Term) antibody
CXCR2 Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (Extracellular Domain) antibody
CXCR2 Reactivity: Human, Monkey IHC, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (AA 1-30), (N-Term) antibody
CXCR2 Reactivity: Human WB, IHC, FACS Host: Rabbit Chimeric SE2 unconjugated Recombinant Antibody

anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (C-Term) antibody
CXCR2 Reactivity: Human, Mouse, Rat WB, IHC, IP Host: Rabbit Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (AA 311-360), (pSer347) antibody
CXCR2 Reactivity: Human, Mouse WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

Application Notes

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date

12 months
Li, Duan, Yu, Dang: "NFATc1 regulates cell proliferation, migration, and invasion of ovarian cancer SKOV3 cells in vitro and in vivo." in: Oncology reports, Vol. 36, Issue 2, pp. 918-28, (2017) (PubMed).

Alexeev, Donahue, Uitto, Igoucheva: "Chemotaxis-driven disease-site targeting of therapeutic adult stem cells in dystrophic epidermolysis bullosa." in: Stem cell research & therapy, Vol. 7, Issue 1, pp. 124, (2016) (PubMed).

Wang, Lu, Dey, Deng, Wu, Jiang, Fang, Zhao, Konaparthi, Hua, Zhang, Li-Ning-Tapia, Kapoor, Wu, Patel, Guo, Ramamoorthy, Tieu, Heffernan, Zhao, Shang, Khadka, Hou, Hu, Jin, Yao, Pan, Ding, Shi, Li et al.: "Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression. ..." in: Cancer discovery, Vol. 6, Issue 1, pp. 80-95, (2016) (PubMed).

Goetzenich, Kraemer, Rossaint, Bleilevens, Dollo, Siry, Rajabi-Alampour, Beckers, Soppert, Lue, Rex, Bernhagen, Stoppe: "The role of macrophage migration inhibitory factor in anesthetic-induced myocardial preconditioning." in: PLoS ONE, Vol. 9, Issue 3, pp. e92827, (2014) (PubMed).
Target

CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Alternative Name

CXCR2/CD182 (CXCR2 Products)

Synonyms

CD182 antibody, CDw128b antibody, CMKAR2 antibody, IL8R2 antibody, IL8RA antibody, IL8RB antibody, CXC-R2 antibody, CXCR-2 antibody, CD128 antibody, CDw128 antibody, Cmkar2 antibody, Gpcr16 antibody, IL-8Rh antibody, IL-8rb antibody, Il8rb antibody, mIL-8RH antibody, C-X-C motif chemokine receptor 2 antibody, chemokine (C-X-C motif) receptor 2 antibody, Cxcr2 antibody, CXCR2 antibody

Background

Synonyms: CD182, IL8R2, IL8RA, IL8RB, CMKAR2, CDw128b, C-X-C chemokine receptor type 2, CXC-R2, CXCR-2, GRO/MGSA receptor, High affinity interleukin-8 receptor B, IL-8R B, IL-8 receptor type 2, CXCR2
Background: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.

Gene ID

3579

UniProt

P25025

Pathways

cAMP Metabolic Process