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COL1A2 antibody (AA 500-600)

COL1A2 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6138839
  • Target See all COL1A2 Antibodies
    COL1A2 (Collagen, Type I, alpha 2 (COL1A2))
    Binding Specificity
    • 13
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 500-600
    Reactivity
    • 61
    • 22
    • 18
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 59
    • 8
    • 6
    • 2
    Rabbit
    Clonality
    • 67
    • 8
    Polyclonal
    Conjugate
    • 44
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This COL1A2 antibody is un-conjugated
    Application
    • 56
    • 31
    • 23
    • 15
    • 11
    • 10
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequence
    PTGDPGKNGD KGHAGLAGAR GAPGPDGNNG AQGPPGPQGV QGGKGEQGPP GPPGFQGLPG PSGPAGEVGK PGERGLHGEF GLPGPAGPRG ERGPPGESGA A
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 500-600 of human Collagen I/COL1A2 (NP_000080.2).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:25 - 1:200
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Jiang, He, Zhu, Liang, Wang, Lu, Ren, Yi, Xiao, Wang: "Endoplasmic reticulum stress-dependent ROS production mediates synovial myofibroblastic differentiation in the immobilization-induced rat knee joint contracture model." in: Experimental cell research, Vol. 369, Issue 2, pp. 325-334, (2018) (PubMed).

    Yu, Zheng, Yang, Fei, Wang, Hou, Sun, Shen: "N-AC-l-Leu-PEI-mediated miR-34a delivery improves osteogenic differentiation under orthodontic force." in: Oncotarget, Vol. 8, Issue 66, pp. 110460-110473, (2017) (PubMed).

    Li, Wan, Zhang, Li, Han: "Quantitative proteomic analysis and comparison of two bone marrow stromal cell lines using the SILAC method." in: Experimental hematology, Vol. 44, Issue 11, pp. 1059-1071, (2017) (PubMed).

  • Target
    COL1A2 (Collagen, Type I, alpha 2 (COL1A2))
    Alternative Name
    COL1A2 (COL1A2 Products)
    Background
    This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.,COL1A2,OI4,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Collagen,Growth factor,Stem Cells,Mesenchymal Stem Cells,COL1A2
    Molecular Weight
    129 kDa
    Gene ID
    1278
    UniProt
    P08123
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