For best experience we recommend to activate Javascript in your browser.

CSNK2A1/CK II alpha antibody (N-Term)

Name: CSNK2A1/CK II alpha antibody (N-Term)
SKU: ABIN6260852
Price: 390.77 USD
Availability: InStock

CSNK2A1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

Western blot analysis of CKII alpha using HepG2 whole cell lysates

IF/ICC

ABIN6277771 at 1/100 staining Mouse lung tissue by IHC-P.

IHC

Western blot analysis of extracts from various samples, using CKII alpha Antibody.

4 images

Catalog No. ABIN6260852

Datasheet as PDF

Target See all CSNK2A1/CK II alpha (CSNK2A1) Antibodies

CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))
Binding Specificity
11

11

7

6

3

3

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
Reactivity
81

56

52

7

6

6

4

4

4

4

3

3

3

2

2

2

1

1

1

1
Human, Mouse, Rat
Host
75

6
Rabbit
Compatible Secondaries
Clonality
73

8
Polyclonal
Conjugate
51

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1
This CSNK2A1/CK II alpha antibody is un-conjugated
Application
68

32

23

9

9

8

3

2

2

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity

CKII alpha Antibody detects endogenous levels of total CKII alpha.

Predicted Reactivity

Pig,Zebrafish,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen

A synthesized peptide derived from human CKII alpha, corresponding to a region within N-terminal amino acids.

Isotype

IgG

Top Product

Discover our top product CSNK2A1 Primary Antibody
anti-Casein Kinase 2 alpha 1 (CSNK2A1) (AA 1-100) antibody
CSNK2A1 Reactivity: Human WB, ELISA, IF, PLA Host: Mouse Monoclonal 3D9 unconjugated

anti-Casein Kinase 2 alpha 1 (CSNK2A1) (AA 1-391) antibody
CSNK2A1 Reactivity: Human WB, ELISA, IHC, IF, IP Host: Rabbit Polyclonal unconjugated

anti-Casein Kinase 2 alpha 1 (CSNK2A1) (AA 250-284) antibody
CSNK2A1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB48211 unconjugated

anti-Casein Kinase 2 alpha 1 (CSNK2A1) antibody
CSNK2A1 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated

anti-Casein Kinase 2 alpha 1 (CSNK2A1) (AA 201-300) antibody
CSNK2A1 Reactivity: Human, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated

anti-Casein Kinase 2 alpha 1 (CSNK2A1) antibody
CSNK2A1 Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Drosophila melanogaster, Monkey, Chinook Salmon (Oncorhynchus tschawytscha), Sheep WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Casein Kinase 2 alpha 1 (CSNK2A1) (AA 28-50), (N-Term) antibody
CSNK2A1 Reactivity: Human, Rat WB Host: Rabbit Polyclonal unconjugated

anti-Casein Kinase 2 alpha 1 (CSNK2A1) (AA 162-195) antibody
CSNK2A1 Reactivity: Human WB Host: Rabbit Polyclonal RB48212 unconjugated

anti-Casein Kinase 2 alpha 1 (CSNK2A1) (AA 240-269) antibody
CSNK2A1 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal RB4025 unconjugated

anti-Casein Kinase 2 alpha 1 (CSNK2A1) antibody
CSNK2A1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

Application Notes

WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date

12 months
Target

CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))

Alternative Name

CSNK2A1 (CSNK2A1 Products)

Synonyms

CK2A2 antibody, CSNK2A1 antibody, CK2A1 antibody, CKII antibody, CSNK2A3 antibody, CK2A antibody, Ck2a antibody, BmCK2a antibody, wu:fi38e04 antibody, wu:fi38h03 antibody, csnk2a1 antibody, CK-II antibody, CK2 antibody, Ckiialpha antibody, Csnk2a1-rs4 antibody, ck2a1 antibody, casein kinase 2 alpha 2 antibody, casein kinase 2 alpha 1 antibody, casein kinase 2 alpha subunit antibody, casein kinase 2, alpha 1 polypeptide antibody, CK2 protein kinase alpha 2 antibody, casein kinase II alpha subunit antibody, Casein kinase II alpha subunit antibody, casein kinase 2, alpha 1 polypeptide S homeolog antibody, CSNK2A2 antibody, CSNK2A1 antibody, ck2a antibody, Ck2a antibody, csnk2a1 antibody, cka2 antibody, Ckiialpha antibody, CK2A1 antibody, Csnk2a1 antibody, csnk2a1.S antibody

Background

Description: Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoint (SAC) that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage. Also required for p53/TP53-mediated apoptosis, phosphorylating 'Ser-392' of p53/TP53 following UV irradiation. Can also negatively regulate apoptosis. Phosphorylates the caspases CASP9 and CASP2 and the apoptotic regulator NOL3. Phosphorylation protects CASP9 from cleavage and activation by CASP8, and inhibits the dimerization of CASP2 and activation of CASP8. Regulates transcription by direct phosphorylation of RNA polymerases I, II, III and IV. Also phosphorylates and regulates numerous transcription factors including NF-kappa-B, STAT1, CREB1, IRF1, IRF2, ATF1, SRF, MAX, JUN, FOS, MYC and MYB. Phosphorylates Hsp90 and its co-chaperones FKBP4 and CDC37, which is essential for chaperone function. Regulates Wnt signaling by phosphorylating CTNNB1 and the transcription factor LEF1. Acts as an ectokinase that phosphorylates several extracellular proteins. During viral infection, phosphorylates various proteins involved in the viral life cycles of EBV, HSV, HBV, HCV, HIV, CMV and HPV. Phosphorylates PML at 'Ser-565' and primes it for ubiquitin-mediated degradation. Plays an important role in the circadian clock function by phosphorylating ARNTL/BMAL1 at 'Ser-90' which is pivotal for its interaction with CLOCK and which controls CLOCK nuclear entry (PubMed:11239457, PubMed:11704824, PubMed:16193064, PubMed:19188443, PubMed:20625391, PubMed:22406621). Phosphorylates CCAR2 at 'Thr-454' in gastric carcinoma tissue (PubMed:24962073).
Gene: CSNK2A1

Molecular Weight

45 kDa

Gene ID

1457

UniProt

P68400

Pathways

SARS-CoV-2 Protein Interactome