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ACMSD antibody (AA 33-129)

ACMSD Reactivity: Human ELISA, WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7142142
  • Target See all ACMSD Antibodies
    ACMSD (Aminocarboxymuconate Semialdehyde Decarboxylase (ACMSD))
    Binding Specificity
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 33-129
    Reactivity
    • 24
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 21
    • 3
    Rabbit
    Clonality
    • 22
    • 2
    Polyclonal
    Conjugate
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACMSD antibody is un-conjugated
    Application
    • 13
    • 10
    • 4
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human, Rat
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase protein (33-129AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    ACMSD (Aminocarboxymuconate Semialdehyde Decarboxylase (ACMSD))
    Alternative Name
    ACMSD (ACMSD Products)
    Synonyms
    zgc:162888 antibody, ACMSD antibody, aminocarboxymuconate semialdehyde decarboxylase antibody, aminocarboxymuconate semialdehyde decarboxylase S homeolog antibody, amino carboxymuconate semialdehyde decarboxylase antibody, ACMSD antibody, acmsd antibody, acmsd.S antibody, Acmsd antibody
    Background

    Background: Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.

    Aliases: 2 amino 3 carboxymuconate 6 semialdehyde decarboxylase antibody, 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase antibody, acmsd antibody, ACMSD_HUMAN antibody, Aminocarboxymuconate semialdehyde decarboxylase antibody, Picolinate carboxylase antibody

    UniProt
    Q8TDX5
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