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DDX3X antibody (AA 518-661)

DDX3X Reactivity: Human, Mouse, Rat, Monkey WB, ELISA, IHC, ICC, FACS Host: Mouse Monoclonal 3B9E3 unconjugated
Catalog No. ABIN5542508
  • Target See all DDX3X Antibodies
    DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))
    Binding Specificity
    • 18
    • 15
    • 9
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 518-661
    Reactivity
    • 103
    • 41
    • 32
    • 5
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Monkey
    Host
    • 95
    • 8
    Mouse
    Clonality
    • 95
    • 7
    Monoclonal
    Conjugate
    • 59
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This DDX3X antibody is un-conjugated
    Application
    • 71
    • 37
    • 32
    • 26
    • 26
    • 17
    • 17
    • 14
    • 11
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human DDX3X (AA: 518-661) expressed in E. coli.
    Clone
    3B9E3
    Isotype
    IgG2a
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))
    Alternative Name
    DDX3X (DDX3X Products)
    Synonyms
    DBX antibody, DDX14 antibody, DDX3 antibody, HLP2 antibody, D1Pas1-rs2 antibody, Ddx3 antibody, Fin14 antibody, An3 antibody, pl10 antibody, DDX3X antibody, DEAD-box helicase 3, X-linked antibody, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked antibody, DEAD-box helicase 3, X-linked L homeolog antibody, DDX3X antibody, Ddx3x antibody, ddx3x.L antibody, ddx3x antibody
    Background

    Description: The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants.,

    Aliases: DBX, DDX3, HLP2, DDX14, CAP-Rf

    Molecular Weight
    73.2 kDa
    Gene ID
    1654
    HGNC
    1654
    Pathways
    Ribonucleoprotein Complex Subunit Organization, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Ribosome Assembly
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