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ELL antibody (Internal Region)

ELL Reactivity: Human, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6257163
  • Target See all ELL Antibodies
    ELL (Elongation Factor RNA Polymerase II (ELL))
    Binding Specificity
    • 15
    • 9
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 56
    • 23
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    Human, Mouse
    Host
    • 54
    • 2
    Rabbit
    Clonality
    • 56
    Polyclonal
    Conjugate
    • 25
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ELL antibody is un-conjugated
    Application
    • 31
    • 21
    • 13
    • 13
    • 7
    • 6
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    ELL Antibody detects endogenous levels of total ELL.
    Predicted Reactivity
    Pig,Zebrafish,Bovine,Horse,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human ELL, corresponding to a region within the internal amino acids.
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    ELL (Elongation Factor RNA Polymerase II (ELL))
    Alternative Name
    ELL (ELL Products)
    Synonyms
    wu:fc60b11 antibody, zgc:63836 antibody, C19orf17 antibody, ELL1 antibody, MEN antibody, PPP1R68 antibody, Ell1 antibody, Men antibody, elongation factor for RNA polymerase II antibody, elongation factor RNA polymerase II antibody, ELL antibody, ell antibody, Ell antibody
    Background

    Description: Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968, PubMed:23932780). Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription (PubMed:23932780). ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation.

    Gene: ELL

    Molecular Weight
    65 kDa
    Gene ID
    8178
    UniProt
    P55199
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