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MECOM antibody

MECOM Reactivity: Human, Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7074575
  • Target See all MECOM Antibodies
    MECOM (MDS1 and EVI1 Complex Locus (MECOM))
    Reactivity
    • 61
    • 23
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 55
    • 13
    • 1
    Rabbit
    Clonality
    • 58
    • 11
    Polyclonal
    Conjugate
    • 34
    • 7
    • 6
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MECOM antibody is un-conjugated
    Application
    • 54
    • 43
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human, Rat
    Purification
    Affinity purification
    Immunogen
    KLH conjugated Synthetic peptide corresponding to Mouse EVI1
  • Application Notes
    WB (H,M) 1:500-1:1000, IHC/IF (M,R) 1:2000-1:4000/1:700-1:1400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    MECOM (MDS1 and EVI1 Complex Locus (MECOM))
    Alternative Name
    EVI1 (MECOM Products)
    Synonyms
    AML1-EVI-1 antibody, EVI1 antibody, MDS1 antibody, MDS1-EVI1 antibody, PRDM3 antibody, D630039M04Rik antibody, Evi-1 antibody, Evi1 antibody, Jbo antibody, Mds antibody, Mds1 antibody, Mds1-Evi1 antibody, Prdm3 antibody, Znfpr1b1 antibody, evi1 antibody, im:7140716 antibody, prdm3 antibody, evi-1 antibody, mecom antibody, mecom-a antibody, mecom-b antibody, xEvi-1 antibody, evi1-B antibody, MDS1 and EVI1 complex locus antibody, MDS1 and EVI1 complex locus L homeolog antibody, MDS1 and EVI1 complex locus S homeolog antibody, MECOM antibody, Mecom antibody, mecom antibody, mecom.L antibody, mecom.S antibody
    Background
    The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
    Molecular Weight
    118 kDa
    Gene ID
    14013
    NCBI Accession
    NP_067417
    UniProt
    P14404