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EXT1 antibody

EXT1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6261628
  • Target See all EXT1 Antibodies
    EXT1 (Exostosin 1 (EXT1))
    Reactivity
    Human, Mouse, Rat
    Host
    • 37
    • 2
    Rabbit
    Clonality
    • 37
    • 2
    Polyclonal
    Conjugate
    • 15
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EXT1 antibody is un-conjugated
    Application
    • 28
    • 18
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificity
    EXT1 Antibody detects endogenous levels of total EXT1
    Cross-Reactivity
    Human, Mouse (Murine), Rat (Rattus)
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human EXT1
    Isotype
    IgG
    Top Product
    Discover our top product EXT1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C.Stable for 12 months from date of receipt
    Expiry Date
    12 months
  • Target
    EXT1 (Exostosin 1 (EXT1))
    Alternative Name
    EXT1 (EXT1 Products)
    Synonyms
    EXT antibody, LGCR antibody, LGS antibody, TRPS2 antibody, TTV antibody, AA409028 antibody, xext1 antibody, fd07d06 antibody, wu:fd07d06 antibody, exostosin glycosyltransferase 1 antibody, exostoses (multiple) 1 antibody, exostosin glycosyltransferase 1b antibody, exostosin like glycosyltransferase 1 antibody, exostosin glycosyltransferase 1 S homeolog antibody, exostosin glycosyltransferase 1a antibody, EXT1 antibody, Ext1 antibody, ext1b antibody, EXTL1 antibody, ext1.S antibody, ext1a antibody
    Background

    Description: Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413).

    Gene: EXT1

    Molecular Weight
    86kDa
    Gene ID
    2131
    UniProt
    Q16394
    Pathways
    Glycosaminoglycan Metabolic Process
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