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APOBEC3D antibody (AA 250-371)

APOBEC3D Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7150152
  • Target See all APOBEC3D Antibodies
    APOBEC3D (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3D (APOBEC3D))
    Binding Specificity
    • 9
    • 8
    • 6
    • 4
    • 1
    • 1
    AA 250-371
    Reactivity
    • 33
    • 11
    • 2
    Human
    Host
    • 32
    • 1
    Rabbit
    Clonality
    • 33
    Polyclonal
    Conjugate
    • 12
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APOBEC3D antibody is un-conjugated
    Application
    • 22
    • 18
    • 3
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human DNA dC->dU-editing enzyme APOBEC-3D protein (250-371AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    APOBEC3D (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3D (APOBEC3D))
    Alternative Name
    APOBEC3D (APOBEC3D Products)
    Synonyms
    A3D antibody, APOBEC3DE antibody, APOBEC3E antibody, ARP6 antibody, APOBEC3D antibody, apolipoprotein B mRNA editing enzyme catalytic subunit 3D antibody, APOBEC3D antibody
    Background

    Background: DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. May inhibit the mobility of LTR and non-LTR retrotransposons.

    Aliases: A3D antibody, ABC3D_HUMAN antibody, APOBEC3D antibody, APOBEC3DE antibody, APOBEC3E antibody, Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3D antibody, Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3E pseudogene antibody, ARP6 antibody, bK150C2.9 antibody, BK150C2.9 protein antibody, DNA dC >dU editing enzyme APOBEC 3D antibody, DNA dC->dU-editing enzyme APOBEC-3D antibody, hCG_41704 antibody, HCG41704, isoform CRA_b antibody, Probable DNA dC->dU-editing enzyme APOBEC-3D antibody

    UniProt
    Q96AK3
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