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COL3 antibody (AA 1301-1400)

COL3 Reactivity: Human, Rat, Mouse, Dog, Rabbit WB, ELISA, IHC (fro), IF (cc), IF (p), IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN669981
  • Target See all COL3 Antibodies
    COL3 (Collagen, Type III (COL3))
    Binding Specificity
    • 15
    • 14
    • 4
    • 1
    • 1
    • 1
    • 1
    AA 1301-1400
    Reactivity
    • 57
    • 41
    • 39
    • 14
    • 14
    • 6
    • 4
    • 1
    Human, Rat, Mouse, Dog, Rabbit
    Host
    • 47
    • 8
    • 7
    Rabbit
    Clonality
    • 54
    • 8
    Polyclonal
    Conjugate
    • 25
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This COL3 antibody is un-conjugated
    Application
    • 51
    • 29
    • 25
    • 25
    • 19
    • 14
    • 11
    • 11
    • 9
    • 6
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody is produced with an immunogen contained within the COLFI propeptide region, it will only recognize the full length Collagen III protein and not the mature form.
    Cross-Reactivity
    Dog, Human, Mouse, Rabbit, Rat
    Predicted Reactivity
    Cow,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Collagen alpha 1(III) chain (C-terminal propeptide)
    Isotype
    IgG
    Top Product
    Discover our top product COL3 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Velázquez, Enos, Carson, Cranford, Bader, Sougiannis, Pritchett, Fan, Carson, Murphy: "miR155 deficiency aggravates high-fat diet-induced adipose tissue fibrosis in male mice." in: Physiological reports, Vol. 5, Issue 18, (2018) (PubMed).

    Bai, Wu, Hong, Zhang, Liu, Chen: "Anti‑fibrotic effect of Sedum sarmentosum Bunge extract in kidneys via the hedgehog signaling pathway." in: Molecular medicine reports, Vol. 16, Issue 1, pp. 737-745, (2017) (PubMed).

    Yu, Liu, Sun, Wang, Wang, Zhao, Dai, Zhao, Zhang, Li, Han, Lu, Dong, Liu, Yu, Li: "Chronic obstructive sleep apnea promotes aortic remodeling in canines through miR-145/Smad3 signaling pathway." in: Oncotarget, Vol. 8, Issue 23, pp. 37705-37716, (2017) (PubMed).

    Yang, Zhao, Wang, Liu, Ma, Huang, Liu: "Isolation and biological characterization of tendon-derived stem cells from fetal bovine." in: In vitro cellular & developmental biology. Animal, Vol. 52, Issue 8, pp. 846-56, (2017) (PubMed).

    Zhu, Hu, Yu, Ren, Hu: "High Molecular Weight Hyaluronic Acid Inhibits Fibrosis of Endometrium." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 22, pp. 3438-3445, (2016) (PubMed).

    Jiang, Chun, Wang, Du, Wang, Xiong: "Effect of transforming growth factor-β3 on the expression of Smad3 and Smad7 in tenocytes." in: Molecular medicine reports, Vol. 13, Issue 4, pp. 3567-73, (2016) (PubMed).

    Bai, Lu, Lin, Xu, Hu, Liang, Hong, Chen: "Sonic hedgehog-mediated epithelial-mesenchymal transition in renal tubulointerstitial fibrosis." in: International journal of molecular medicine, Vol. 37, Issue 5, pp. 1317-27, (2016) (PubMed).

    Su, Zhao, Shi, Zhang, Yu, Xie, Guo, Zhang, Liu, Shen, Wang, Li, Zhang, Zhou: "Let-7d suppresses growth, metastasis, and tumor macrophage infiltration in renal cell carcinoma by targeting COL3A1 and CCL7." in: Molecular cancer, Vol. 13, pp. 206, (2016) (PubMed).

    Wang, Li, Huang, Wang: "The influence of hypoxia during different pregnancy stages on cardiac collagen accumulation in the adult offspring." in: BioMed research international, Vol. 2014, pp. 419805, (2015) (PubMed).

    Zhao, Zhang, Chen, Gu, Ni, Shao, Wu, Qin: "Increased expression of NF-AT3 and NF-AT4 in the atria correlates with procollagen I carboxyl terminal peptide and TGF-β1 levels in serum of patients with atrial fibrillation." in: BMC cardiovascular disorders, Vol. 14, pp. 167, (2015) (PubMed).

  • Target
    COL3 (Collagen, Type III (COL3))
    Alternative Name
    Collagen 3 (COL3 Products)
    Synonyms
    PT antibody, RPRGL2 antibody, THPH1 antibody, Cf-2 antibody, Cf2 antibody, FII antibody, thrombin antibody, prothrombin antibody, coagulation factor II, thrombin antibody, coagulation factor II antibody, F2 antibody
    Background

    Synonyms: EDS4A, Collagen alpha-1(III) chain, COL3A1

    Background: Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of GPR56 in the developing brain and binding to GPR56 inhibits neuronal migration and activates the RhoA pathway by coupling GPR56 to GNA13 and possibly GNA12.

    Gene ID
    1281
    UniProt
    P02461
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