FLT3 antibody (AA 62-295)
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- Target See all FLT3 Antibodies
- FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
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Binding Specificity
- AA 62-295
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FLT3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- Rabbit IgG polyclonal antibody for Flt3 / CD135 detection. Tested with WB, IHC-P, Direct ELISA in Mouse,Rat.
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
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Rabbit IgG polyclonal antibody for Flt3 / CD135 detection. Tested with WB, IHC-P, Direct ELISA in Mouse,Rat.
Gene Name: FMS-like tyrosine kinase 3
Protein Name: Receptor-type tyrosine-protein kinase FLT3 - Purification
- Immunogen affinity purified.
- Immunogen
- E. coli-derived mouse Flt3 / CD135 recombinant protein (Position: E62-E295).
- Isotype
- IgG
- Top Product
- Discover our top product FLT3 Primary Antibody
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anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 930-991) antibody
FLT3 Reactivity: Human WB, ELISA, IHC Host: Mouse Monoclonal 7B7C3 unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) antibodyFLT3 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 334-543) antibodyFLT3 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 335-544) antibodyFLT3 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 33-64), (N-Term) antibodyFLT3 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB01544 unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 33-64) antibodyFLT3 Reactivity: Human WB, ELISA, IHC, FACS Host: Rabbit Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (C-Term) antibodyFLT3 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (FITC)FLT3 Reactivity: Human FACS Host: Mouse Monoclonal BV10A4 FITC
anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (PE)FLT3 Reactivity: Human FACS Host: Mouse Monoclonal BV10A4 PE
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 650-750) antibodyFLT3 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
- Comment
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Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
- Alternative Name
- Flt3 (FLT3 Products)
- Synonyms
- FLT3 antibody, B230315G04 antibody, CD135 antibody, Flk-2 antibody, Flk2 antibody, Flt-3 antibody, Ly72 antibody, wmfl antibody, FLK-2 antibody, FLK2 antibody, STK1 antibody, fms related tyrosine kinase 3 antibody, FMS-like tyrosine kinase 3 antibody, fms-related tyrosine kinase 3 antibody, FLT3 antibody, Flt3 antibody
- Background
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Cluster of differentiation antigen 135 (CD135) also known as fms like tyrosine kinase 3 (FLT-3), receptor-type tyrosine-protein kinase FLT3, or fetal liver kinase-2 (Flk2) is a protein that in humans is encoded by the FLT3 gene. This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow.
Synonyms: Receptor-type tyrosine-protein kinase FLT3, FL cytokine receptor, Fetal liver kinase 2, FLK-2, Fms-like tyrosine kinase 3, FLT-3, Tyrosine-protein kinase receptor flk-2, CD135, Flt3, Flk-2, Flt-3 - Gene ID
- 14255
- UniProt
- Q00342
- Pathways
- RTK Signaling
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