FZD4 antibody (Middle Region)
(3 references)-
- Target See all FZD4 Antibodies
- FZD4 (Frizzled Family Receptor 4 (FZD4))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Horse, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FZD4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- GITSGMWIWS AKTLHTWQKC SNRLVNSGKV KREKRGNGWV KPGKGSETVV
- Predicted Reactivity
- Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against FZD4. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human FZD4
- Top Product
- Discover our top product FZD4 Primary Antibody
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anti-Frizzled Family Receptor 4 (FZD4) (AA 37-222) antibody
FZD4 Reactivity: Human WB, ELISA, IHC, FACS, ICC, Neut Host: Mouse Monoclonal 2F3A7 unconjugated
anti-Frizzled Family Receptor 4 (FZD4) (AA 11-60) antibodyFZD4 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Frizzled Family Receptor 4 (FZD4) (AA 37-222) antibodyFZD4 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Frizzled Family Receptor 4 (FZD4) (AA 100-200) antibodyFZD4 Reactivity: Human, Mouse WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Frizzled Family Receptor 4 (FZD4) (AA 107-206) antibodyFZD4 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3G7 unconjugated
anti-Frizzled Family Receptor 4 (FZD4) (AA 100-200) antibody (HRP)FZD4 Reactivity: Human, Mouse WB, IHC Host: Rabbit Polyclonal HRP
anti-Frizzled Family Receptor 4 (FZD4) (AA 100-200) antibody (FITC)FZD4 Reactivity: Human, Mouse WB, IHC Host: Rabbit Polyclonal FITC
anti-Frizzled Family Receptor 4 (FZD4) (AA 100-200) antibody (Alkaline Phosphatase (AP))FZD4 Reactivity: Human, Mouse WB, IHC Host: Rabbit Polyclonal Alkaline Phosphatase (AP)
anti-Frizzled Family Receptor 4 (FZD4) (AA 100-200) antibody (Biotin)FZD4 Reactivity: Human, Mouse WB, IHC Host: Rabbit Polyclonal Biotin
anti-Frizzled Family Receptor 4 (FZD4) (AA 100-200) antibody (PE)FZD4 Reactivity: Human, Mouse WB, IHC Host: Rabbit Polyclonal PE
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 537 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Impact of laminitis on the canonical Wnt signaling pathway in basal epithelial cells of the equine digital laminae." in: PLoS ONE, Vol. 8, Issue 2, pp. e56025, (2013) (PubMed).
: "A unique combination of male germ cell miRNAs coordinates gonocyte differentiation." in: PLoS ONE, Vol. 7, Issue 4, pp. e35553, (2012) (PubMed).
: "Spatio-temporal expression pattern of frizzled receptors after contusive spinal cord injury in adult rats." in: PLoS ONE, Vol. 7, Issue 12, pp. e50793, (2012) (PubMed).
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: "Impact of laminitis on the canonical Wnt signaling pathway in basal epithelial cells of the equine digital laminae." in: PLoS ONE, Vol. 8, Issue 2, pp. e56025, (2013) (PubMed).
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- Target
- FZD4 (Frizzled Family Receptor 4 (FZD4))
- Alternative Name
- FZD4 (FZD4 Products)
- Synonyms
- CG4626 antibody, DFz4 antibody, Dfz4 antibody, Dm Fz4 antibody, Dmel\\CG4626 antibody, Fz4 antibody, anon-WO0170980.10 antibody, anon-WO0170980.11 antibody, fz1 antibody, zg01 antibody, CD344 antibody, EVR1 antibody, FEVR antibody, FZD4S antibody, Fz-4 antibody, FzE4 antibody, GPCR antibody, hFz4 antibody, frizzled4 antibody, fz4 antibody, FZ-4 antibody, frizzled 4 antibody, frizzled class receptor 4 antibody, frizzled-4 antibody, frizzled class receptor 4 S homeolog antibody, fz4 antibody, fzd4 antibody, Tsp_10376 antibody, FZD4 antibody, Fzd4 antibody, fzd4.S antibody
- Background
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FZD4 is a member of the frizzled family. Members of this family are seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: EVR1, FEVR, FZD4S, Fz-4, FzE4, GPCR, MGC34390, CD344
Protein Interaction Partner: UBC, NDP, ZNRF3, BAG6, MAGI3, DLG2, DLG4, DVL2, DLG1, ARRB2,
Protein Size: 537 - Molecular Weight
- 60 kDa
- Gene ID
- 8322
- NCBI Accession
- NM_012193, NP_036325
- UniProt
- Q9ULV1
- Pathways
- WNT Signaling, Hormone Transport, Sensory Perception of Sound
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