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GATA1 antibody (pSer142)

GATA1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, IP, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6254982
  • Target See all GATA1 Antibodies
    GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))
    Binding Specificity
    • 32
    • 26
    • 16
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer142
    Reactivity
    • 108
    • 64
    • 44
    • 11
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 119
    • 7
    • 2
    Rabbit
    Clonality
    • 113
    • 15
    Polyclonal
    Conjugate
    • 60
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This GATA1 antibody is un-conjugated
    Application
    • 102
    • 40
    • 39
    • 37
    • 20
    • 18
    • 17
    • 16
    • 16
    • 10
    • 9
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    Specificity
    Phospho-GATA1 (Ser142) Antibody detects endogenous levels of GATA1 only when phosphorylated at Serine 142.
    Predicted Reactivity
    Pig,Sheep,Rabbit
    Purification
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogen
    A synthesized peptide derived from human GATA1 around the phosphorylation site of Ser142.
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, IP, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))
    Alternative Name
    GATA1 (GATA1 Products)
    Synonyms
    ERYF1 antibody, GATA-1 antibody, GF-1 antibody, GF1 antibody, NF-E1 antibody, NFE1 antibody, XLANP antibody, XLTDA antibody, XLTT antibody, Gata-1 antibody, Gf-1 antibody, eryf1 antibody, Eryf1 antibody, GATA1 antibody, gata-1 antibody, Gata1 antibody, si:dkeyp-77f7.5 antibody, gata1 antibody, gata1a-A antibody, xGATA-1 antibody, xgata1 antibody, XGATA-1B antibody, gata1b-A antibody, gta1 antibody, zg1 antibody, NF-E1a antibody, GATA binding protein 1 antibody, GATA binding protein 1 (globin transcription factor 1) antibody, amidase antibody, aspartyl/glutamyl-tRNA amidotransferase subunit A antibody, putative amidase antibody, GatA1 antibody, glutamyl-tRNA amidotransferase subunit A antibody, hematopietic transcription factor GATA-1 antibody, GATA binding protein 1b antibody, GATA binding protein 1 L homeolog antibody, GATA binding protein 1 S homeolog antibody, GATA binding protein 1a antibody, erythroid transcription factor antibody, GATA1 antibody, Gata1 antibody, gatA1 antibody, gata-1 antibody, gata1b antibody, gata1.L antibody, gata1.S antibody, gata1a antibody, LOC108348091 antibody
    Background

    Description: Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS (PubMed:24245781).

    Gene: GATA1

    Molecular Weight
    43kDa
    Gene ID
    2623
    UniProt
    P15976
    Pathways
    Cellular Response to Molecule of Bacterial Origin
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