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GFI1 antibody

GFI1 Reactivity: Human, Rat, Mouse ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7245050
  • Target See all GFI1 Antibodies
    GFI1 (Growth Factor Independent 1 (GFI1))
    Reactivity
    • 22
    • 15
    • 14
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 17
    • 6
    Rabbit
    Clonality
    • 19
    • 4
    Polyclonal
    Conjugate
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GFI1 antibody is un-conjugated
    Application
    • 16
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogen
    Synthetic peptide of human GFI1
    Isotype
    IgG
    Top Product
    Discover our top product GFI1 Primary Antibody
  • Application Notes
    IHC 1:50-1:300, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.62 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    GFI1 (Growth Factor Independent 1 (GFI1))
    Alternative Name
    GFI1 (GFI1 Products)
    Synonyms
    AW495828 antibody, Gfi-1 antibody, Pal-1 antibody, Pal1 antibody, GFI1 antibody, GFI-1 antibody, GFI1A antibody, SCN2 antibody, ZNF163 antibody, growth factor independent 1 antibody, growth factor independent 1 transcriptional repressor antibody, Gfi1 antibody, GFI1 antibody
    Background
    This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.
    UniProt
    Q99684
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