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Growth Hormone Receptor antibody (AA 101-200)

Name: Growth Hormone Receptor antibody (AA 101-200)
SKU: ABIN671481
Price: 384.62 USD
Availability: InStock

GHR Reactivity: Human, Mouse, Rat, Pig, Sheep WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

Evaluation of the pig GHR transcript with a 4bp insert in vitro.

Formalin-fixed and paraffin embedded rat liver tissue labeled Anti-GHR Polyclonal Antibody, Unconjugated (ABIN671481) at 1:400, followed by conjugation to the secondary antibody and DAB staining

IHC

Human A549 cell lysates probed with Rabbit Anti-GHR Polyclonal Antibody, Unconjugated .

FACS

This image was generously provided by Brandon Menzies, PhD, from The University of Melbourne.

IHC (p)

Formalin-fixed and paraffin embedded rat liver tissue labeled Anti-GHR Polyclonal Antibody, Unconjugated at 1:400, followed by conjugation to the secondary antibody and DAB staining

IHC (p)

Knockout of the pig GHR gene in F2 homozygous pigs (GHR4bp/4bp refers to -/-).

6 images

(7 references)

Catalog No. ABIN671481

Datasheet as PDF

Target See all Growth Hormone Receptor (GHR) Antibodies

Growth Hormone Receptor (GHR)
Binding Specificity
15

5

4

3

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 101-200
Reactivity
53

31

31

16

15

2

1
Human, Mouse, Rat, Pig, Sheep
Host
52

4
Rabbit
Compatible Secondaries
Clonality
43

13
Polyclonal
Conjugate
25

4

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1
This Growth Hormone Receptor antibody is un-conjugated
Application
37

18

14

13

13

7

5

5

3

3

1

1

1

1

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity

Human, Mouse, Pig, Rat, Sheep

Predicted Reactivity

Dog,Cow,Chicken

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human GHR

Isotype

IgG
anti-Growth Hormone Receptor (GHR) (AA 353-588) antibody
GHR Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Growth Hormone Receptor (GHR) antibody
GHR Reactivity: Human ELISA, IHC, IF Host: Rabbit Monoclonal 10C11 unconjugated Recombinant Antibody

anti-Growth Hormone Receptor (GHR) (AA 19-118) antibody
GHR Reactivity: Human WB, ELISA, PLA Host: Mouse Monoclonal 3A12 unconjugated

anti-Growth Hormone Receptor (GHR) (AA 315-574) antibody
GHR Reactivity: Human WB, ELISA, ICC, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Growth Hormone Receptor (GHR) (AA 36-266) antibody
GHR Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Growth Hormone Receptor (GHR) (N-Term) antibody
GHR Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated

anti-Growth Hormone Receptor (GHR) (AA 19-184) antibody
GHR Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-Growth Hormone Receptor (GHR) (AA 19-118) antibody
GHR Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated

anti-Growth Hormone Receptor (GHR) antibody
GHR Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated

anti-Growth Hormone Receptor (GHR) (AA 36-85) antibody
GHR Reactivity: Human WB Host: Rabbit Polyclonal unconjugated

Application Notes

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date

12 months
Zhou, Yang, Yang, Huang, Zhou, Jiang, Yang: "Effects of zearalenone on the localization and expression of the growth hormone receptor gene in the uteri of post-weaning piglets." in: Asian-Australasian journal of animal sciences, Vol. 31, Issue 1, pp. 32-39, (2018) (PubMed).

Zhao, Feng, Zhang, Kou, Li, Liu, Zhang, Cui, Chu, Shen, Min: "Inhibition of peripubertal sheep mammary gland development by cysteamine through reducing progesterone and growth factor production." in: Theriogenology, Vol. 89, pp. 280-288, (2017) (PubMed).

Chu, Zhao, Feng, Zhang, Liu, Cheng, Li, Shen, Cao, Li, Min: "MicroRNA-126 participates in lipid metabolism in mammary epithelial cells." in: Molecular and cellular endocrinology, Vol. 454, pp. 77-86, (2017) (PubMed).

Hetz, Menzies, Shaw, Rao, Clarke, Renfree: "Growth axis maturation is linked to nutrition, growth and developmental rate." in: Molecular and cellular endocrinology, Vol. 411, pp. 38-48, (2015) (PubMed).

Song, Yang, Tang, Chen: "Effects of sericin on the testicular growth hormone/insulin-like growth factor-1 axis in a rat model of type 2 diabetes." in: International journal of clinical and experimental medicine, Vol. 8, Issue 7, pp. 10411-9, (2015) (PubMed).

Yang, Sun, Sun, Qi: "Effect of suppressor of cytokine signaling 2 (SOCS2) on fat metabolism induced by growth hormone (GH) in porcine primary adipocyte." in: Molecular biology reports, Vol. 39, Issue 9, pp. 9113-22, (2012) (PubMed).

Wang, Zhou, Lin, Wang, Lin, Li: "RhGH attenuates ischemia injury of intrahepatic bile ducts relating to liver transplantation." in: The Journal of surgical research, Vol. 171, Issue 1, pp. 300-10, (2011) (PubMed).
Target

Growth Hormone Receptor (GHR)

Alternative Name

GHR (GHR Products)

Synonyms

GHBP antibody, AA986417 antibody, GHR/BP antibody, GHR antibody, ghr antibody, ghr.a antibody, zgc:162141 antibody, growth hormone receptor antibody, growth hormone receptor L homeolog antibody, growth hormone receptor a antibody, GHR antibody, Ghr antibody, ghr.L antibody, ghr antibody, ghra antibody

Background

Synonyms: GHBP, Growth hormone receptor, GH receptor, Somatotropin receptor, GHR
Background: Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity). The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.

Gene ID

2690

UniProt

P10912

Pathways

NF-kappaB Signaling, JAK-STAT Signaling, Response to Growth Hormone Stimulus