NG2 antibody (AA 2247-2308)
(2 references)-
- Target See all NG2 (MCSP) Antibodies
- NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
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Binding Specificity
- AA 2247-2308
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This NG2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human CSPG4 (AA: 2247-2308) expressed in E. coli.
- Clone
- 7G4E5
- Isotype
- IgG1
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anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) (AA 1919-2258) antibody
MCSP Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) (AA 1950-2210) antibodyMCSP Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) (AA 559-776) antibodyMCSP Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal 6# unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) (AA 1950-2210) antibodyMCSP Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) antibodyMicroarray verified MCSP Reactivity: Human, Mouse IHC Host: Mouse Monoclonal MAB41136 unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) antibodyMicroarray verified MCSP Reactivity: Human, Mouse IHC Host: Mouse Monoclonal MAB300756 unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) antibodyMCSP Reactivity: Human WB, IP, ICC, FACS Host: Mouse Monoclonal 7-1 unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) antibody (APC)MCSP Reactivity: Human FACS Host: Mouse Monoclonal 7-1 APC
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) antibody (PE)MCSP Reactivity: Human FACS Host: Mouse Monoclonal 7-1 PE
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) antibodyMCSP Reactivity: Human WB Host: Rabbit Monoclonal unconjugated
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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: "Functional characterization of an scFv-Fc antibody that immunotherapeutically targets the common cancer cell surface proteoglycan CSPG4." in: Cancer research, Vol. 71, Issue 24, pp. 7410-22, (2011) (PubMed).
: "CSPG4, a potential therapeutic target, facilitates malignant progression of melanoma." in: Pigment cell & melanoma research, Vol. 24, Issue 6, pp. 1148-57, (2011) (PubMed).
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: "Functional characterization of an scFv-Fc antibody that immunotherapeutically targets the common cancer cell surface proteoglycan CSPG4." in: Cancer research, Vol. 71, Issue 24, pp. 7410-22, (2011) (PubMed).
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- Target
- NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
- Alternative Name
- CSPG4 (MCSP Products)
- Synonyms
- HMW-MAA antibody, MCSP antibody, MCSPG antibody, MEL-CSPG antibody, MSK16 antibody, NG2 antibody, 4732461B14Rik antibody, AN2 antibody, Ng2 antibody, HSMCSGEN1 antibody, MCS antibody, chondroitin sulfate proteoglycan 4 antibody, sperm mitochondria associated cysteine rich protein antibody, CSPG4 antibody, Cspg4 antibody, SMCP antibody
- Background
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Description: A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.
Aliases: NG2, MCSP, MCSPG, MSK16, HMW-MAA, MEL-CSPG
- Molecular Weight
- 250.0 kDa
- Gene ID
- 1464
- HGNC
- 1464
- Pathways
- Glycosaminoglycan Metabolic Process
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