GNAI3 antibody (N-Term)
(1 reference)-
- Target See all GNAI3 Antibodies
- GNAI3 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 3 (GNAI3))
-
Binding Specificity
- N-Term
-
Reactivity
- Human, Rat, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This GNAI3 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- GNAI3 Antibody detects endogenous levels of total GNAI3.
- Predicted Reactivity
- Pig,Zebrafish,Bovine,Sheep,Rabbit,Dog,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human GNAI3, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product GNAI3 Primary Antibody
-
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 3 (GNAI3) (AA 1-354) antibody
GNAI3 Reactivity: Human WB, IF, IP Host: Rabbit Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 3 (GNAI3) (AA 1-354) antibodyGNAI3 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 3 (GNAI3) antibodyGNAI3 Reactivity: Human, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 3 (GNAI3) (AA 181-230) antibodyGNAI3 Reactivity: Human, Rat, Mouse, Zebrafish (Danio rerio), Horse, Rabbit, Cow, Dog, Guinea Pig, Hamster, Monkey, Chicken, Drosophila melanogaster, Pig, Xenopus laevis WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 3 (GNAI3) antibodyGNAI3 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 3 (GNAI3) (AA 309-343) antibodyGNAI3 Reactivity: Human WB Host: Rabbit Polyclonal RB46791 unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 3 (GNAI3) antibodyGNAI3 Reactivity: Human, Rat, Mouse IF Host: Rabbit Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 3 (GNAI3) (AA 43-92) antibodyGNAI3 Reactivity: Human, Rat, Mouse, Zebrafish (Danio rerio), Hamster, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 3 (GNAI3) (AA 1-100) antibodyGNAI3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 3 (GNAI3) (N-Term) antibodyGNAI3 Reactivity: Human, Rat, Mouse, Zebrafish (Danio rerio), Horse, Rabbit, Cow, Dog, Guinea Pig, Sheep, Goat WB Host: Rabbit Polyclonal unconjugated
-
- Application Notes
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
-
-
: "Identification of BiP as a CB1 Receptor-Interacting Protein That Fine-Tunes Cannabinoid Signaling in the Mouse Brain. ..." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 41, Issue 38, pp. 7924-7941, (2021) (PubMed).
-
: "Identification of BiP as a CB1 Receptor-Interacting Protein That Fine-Tunes Cannabinoid Signaling in the Mouse Brain. ..." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 41, Issue 38, pp. 7924-7941, (2021) (PubMed).
-
- Target
- GNAI3 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 3 (GNAI3))
- Alternative Name
- GNAI3 (GNAI3 Products)
- Synonyms
- AI158965 antibody, AW537698 antibody, Galphai3 antibody, Gnai-3 antibody, 87U6 antibody, ARCND1 antibody, GIP3A antibody, G protein subunit alpha i3 antibody, guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 antibody, guanine nucleotide binding protein (G protein), alpha inhibiting 3 antibody, G protein subunit alpha i3 S homeolog antibody, GNAI3 antibody, gnai3 antibody, Gnai3 antibody, gnai3.S antibody
- Background
-
Description: Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins (PubMed:8774883, PubMed:18434541, PubMed:19478087). Signaling is mediated via effector proteins, such as adenylate cyclase. Inhibits adenylate cyclase activity, leading to decreased intracellular cAMP levels (PubMed:19478087). Stimulates the activity of receptor-regulated K+ channels (PubMed:2535845). The active GTP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division (PubMed:17635935).
Gene: GNAI3
- Molecular Weight
- 41 kDa
- Gene ID
- 2773
- UniProt
- P08754
- Pathways
- cAMP Metabolic Process, G-protein mediated Events
-
