PIK3R6 antibody (Regulatory Subunit 6)
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- Target See all PIK3R6 Antibodies
- PIK3R6 (Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6))
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Binding Specificity
- AA 566-667, Regulatory Subunit 6
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PIK3R6 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Phosphoinositide 3-kinase regulatory subunit 6 protein (566-667AA)
- Isotype
- IgG
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anti-Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6) (C-Term) antibody
PIK3R6 Reactivity: Human WB, ELISA, IF, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6) (AA 661-754) antibodyPIK3R6 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6) (AA 661-754) antibodyPIK3R6 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1G16 unconjugated
anti-Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6) (AA 661-754) antibodyPIK3R6 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2F18 unconjugated
anti-Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6) (Center) antibodyPIK3R6 Reactivity: Human, Rat, Mouse WB Host: Rabbit Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6) (C-Term) antibodyPIK3R6 Reactivity: Human, Rat, Mouse, Guinea Pig, Horse, Pig WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- PIK3R6 (Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6))
- Alternative Name
- PIK3R6 (PIK3R6 Products)
- Synonyms
- C17orf38 antibody, HsT41028 antibody, p84 antibody, p84 PIKAP antibody, p87(PIKAP) antibody, p87PIKAP antibody, BB220380 antibody, RGD1560850 antibody, phosphoinositide-3-kinase regulatory subunit 6 antibody, phosphoinositide-3-kinase regulatory subunit 5 antibody, phosphoinositide-3-kinase, regulatory subunit 6 antibody, PIK3R6 antibody, Pik3r6 antibody
- Background
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Background: Regulatory subunit of the PI3K gamma complex. Acts as an adapter to drive activation of PIK3CG by beta-gamma G protein dimers. The PIK3CG:PIK3R6 heterodimer is much less sensitive to beta-gamma G protein dimers than PIK3CG:PIK3R5 and its membrane recruitment and beta-gamma G protein dimer-dependent activation requires HRAS bound to PIK3CG. Recruits of the PI3K gamma complex to a PDE3B:RAPGEF3 signaling complex involved in angiogenesis, signaling seems to involve RRAS.
Aliases: C17orf38 antibody, Chromosome 17 open reading frame 38 antibody, HsT41028 antibody, p84 PI3K adapter protein antibody, p84 PIKAP antibody, p87 phosphoinositide 3-kinase gamma (PI3Kg) adapter protein antibody, p87 PI3K adapter protein antibody, p87PIKAP antibody, Phosphatidylinositol 3-kinase, regulatory subunit 6 antibody, Phosphoinositide 3-kinase gamma adapter protein of 87 kDa antibody, Phosphoinositide 3-kinase regulatory subunit 6 antibody, PI3Kgamma adapter protein of 87 kDa antibody, PI3R6_HUMAN antibody, PIK3R6 antibody
- UniProt
- Q5UE93
- Pathways
- PI3K-Akt Signaling, Inositol Metabolic Process
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