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STARD6 antibody (C-Term)

STARD6 Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB29820 unconjugated
Catalog No. ABIN655777
  • Target See all STARD6 Antibodies
    STARD6 (StAR-Related Lipid Transfer (START) Domain Containing 6 (STARD6))
    Binding Specificity
    • 7
    • 7
    • 7
    • 1
    AA 187-215, C-Term
    Reactivity
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 15
    Rabbit
    Clonality
    • 15
    Polyclonal
    Conjugate
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    This STARD6 antibody is un-conjugated
    Application
    • 15
    • 12
    • 12
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This STARD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-215 amino acids from the C-terminal region of human STARD6.
    Clone
    RB29820
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • LaVoie, Whitfield, Shi, King, Bose, Hui: "STARD6 is expressed in steroidogenic cells of the ovary and can enhance de novo steroidogenesis." in: Experimental biology and medicine (Maywood, N.J.), Vol. 239, Issue 4, pp. 430-5, (2014) (PubMed).

  • Target
    STARD6 (StAR-Related Lipid Transfer (START) Domain Containing 6 (STARD6))
    Alternative Name
    STARD6 (STARD6 Products)
    Synonyms
    1700011K09Rik antibody, 4833424I06Rik antibody, 4933429L05Rik antibody, AI644424 antibody, StAR related lipid transfer domain containing 6 antibody, StAR-related lipid transfer (START) domain containing 6 antibody, STARD6 antibody, Stard6 antibody
    Background
    Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1, MIM 184756) and by liver X receptors (e.g., LXRA, MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR, MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD6 (Soccio et al., 2002 [PubMed 12011452]).
    Gene ID
    147323
    NCBI Accession
    NP_631910
    UniProt
    P59095
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