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GRK5 antibody (C-Term)

Name: GRK5 antibody (C-Term)
SKU: ABIN390988
Price: 429 USD
Availability: InStock

GRK5 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB0903 unconjugated

All lanes : Anti-GRK5 Antibody at 1:2000 dilution Lane 1: Hela whole cell lysates Lane 2: HepG2 whole cell lysates Lane 3: Ramos whole cell lysates Lysates/proteins at 20 μg per lane.

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with GRK5 Antibody (C-term) (ABIN390988 and ABIN2841171) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

IHC (p)

Western blot analysis of anti-GRK5 Pab (ABIN390988 and ABIN2841171) in mouse brain tissue lysate.

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

IHC (p)

5 images

Catalog No. ABIN390988

Datasheet as PDF

Target See all GRK5 Antibodies

GRK5 (G Protein-Coupled Receptor Kinase 5 (GRK5))
Binding Specificity
9

7

6

4

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 559-590, C-Term
Reactivity
48

31

21

8

5

5

4

4

4

4

4

2

1

1

1
Human, Mouse
Host
46

2

1
Rabbit
Compatible Secondaries
Clonality
47

2
Polyclonal
Conjugate
28

4

4

3

2

2

1

1

1

1

1

1
This GRK5 antibody is un-conjugated
Application
32

26

24

8

3

2

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity

B

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen

This GRK5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 559-590 amino acids from the C-terminal region of human GRK5.

Clone

RB0903

Isotype

Ig Fraction
anti-G Protein-Coupled Receptor Kinase 5 (GRK5) (AA 371-590) antibody
GRK5 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-G Protein-Coupled Receptor Kinase 5 (GRK5) antibody
GRK5 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated

anti-G Protein-Coupled Receptor Kinase 5 (GRK5) (AA 406-590) antibody
GRK5 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-G Protein-Coupled Receptor Kinase 5 (GRK5) (Internal Region) antibody
GRK5 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-G Protein-Coupled Receptor Kinase 5 (GRK5) (AA 393-429), (C-Term) antibody
GRK5 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-G Protein-Coupled Receptor Kinase 5 (GRK5) (Internal Region) antibody
GRK5 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-G Protein-Coupled Receptor Kinase 5 (GRK5) (Internal Region) antibody
GRK5 Reactivity: Human, Mouse, Rat, Cow, Horse, Chicken, Monkey, Pig, Bat IHC, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-G Protein-Coupled Receptor Kinase 5 (GRK5) (N-Term) antibody
GRK5 Reactivity: Human, Cow, Dog IHC, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-G Protein-Coupled Receptor Kinase 5 (GRK5) (C-Term) antibody
GRK5 Reactivity: Human, Mouse WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-G Protein-Coupled Receptor Kinase 5 (GRK5) (AA 290-339) antibody
GRK5 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio), Chicken, Monkey, Pig WB Host: Rabbit Polyclonal unconjugated

Application Notes

WB: 1:2000. WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date

6 months
Target

GRK5 (G Protein-Coupled Receptor Kinase 5 (GRK5))

Alternative Name

GRK5 (GRK5 Products)

Synonyms

GPRK5 antibody, Gprk5 antibody, si:dkey-171l20.1 antibody, GRK5 antibody, DKFZp468J1119 antibody, grk5 antibody, G protein-coupled receptor kinase 5 antibody, G protein-coupled receptor kinase 5 L homeolog antibody, GRK5 antibody, Grk5 antibody, grk5 antibody, grk5.L antibody

Background

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).

Molecular Weight

67787

Gene ID

2869

NCBI Accession

NP_005299

UniProt

P34947

Pathways

Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling