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SPC24 antibody (AA 21-97)

SPC24 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7157667
  • Target See all SPC24 Antibodies
    SPC24 (SPC24, NDC80 Kinetochore Complex Component, Homolog (SPC24))
    Binding Specificity
    • 4
    • 1
    • 1
    AA 21-97
    Reactivity
    • 8
    • 2
    Human
    Host
    • 8
    Rabbit
    Clonality
    • 8
    Polyclonal
    Conjugate
    • 4
    • 2
    • 1
    • 1
    This SPC24 antibody is un-conjugated
    Application
    ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Kinetochore protein Spc24 protein (21-97AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SPC24 (SPC24, NDC80 Kinetochore Complex Component, Homolog (SPC24))
    Alternative Name
    SPC24 (SPC24 Products)
    Synonyms
    SPBC24 antibody, spbc24 antibody, 2410030K01Rik antibody, AV109292 antibody, Spbc24 antibody, wu:fb79a02 antibody, zgc:110417 antibody, SPC24, NDC80 kinetochore complex component antibody, SPC24, NDC80 kinetochore complex component L homeolog antibody, SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) antibody, SPC24 antibody, spc24.L antibody, Spc24 antibody, spc24 antibody
    Background

    Background: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:14738735). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:14738735). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020).

    Aliases: FLJ90806 antibody, hSpc24 antibody, Kinetochore protein Spc24 antibody, SPBC24 antibody, spc24 antibody, SPC24 NDC80 kinetochore complex component antibody, SPC24 NDC80 kinetochore complex component homolog antibody, SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) antibody, SPC24_HUMAN antibody, Spindle pole body component 24 homolog (S. cerevisiae) antibody, Spindle pole body component 24 homolog antibody

    UniProt
    Q8NBT2
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