SPC24 antibody (AA 21-97)
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- Target See all SPC24 Antibodies
- SPC24 (SPC24, NDC80 Kinetochore Complex Component, Homolog (SPC24))
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Binding Specificity
- AA 21-97
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SPC24 antibody is un-conjugated
- Application
- ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Kinetochore protein Spc24 protein (21-97AA)
- Isotype
- IgG
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- Application Notes
- Recommended dilution: IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SPC24 (SPC24, NDC80 Kinetochore Complex Component, Homolog (SPC24))
- Alternative Name
- SPC24 (SPC24 Products)
- Synonyms
- SPBC24 antibody, spbc24 antibody, 2410030K01Rik antibody, AV109292 antibody, Spbc24 antibody, wu:fb79a02 antibody, zgc:110417 antibody, SPC24, NDC80 kinetochore complex component antibody, SPC24, NDC80 kinetochore complex component L homeolog antibody, SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) antibody, SPC24 antibody, spc24.L antibody, Spc24 antibody, spc24 antibody
- Background
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Background: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:14738735). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:14738735). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020).
Aliases: FLJ90806 antibody, hSpc24 antibody, Kinetochore protein Spc24 antibody, SPBC24 antibody, spc24 antibody, SPC24 NDC80 kinetochore complex component antibody, SPC24 NDC80 kinetochore complex component homolog antibody, SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) antibody, SPC24_HUMAN antibody, Spindle pole body component 24 homolog (S. cerevisiae) antibody, Spindle pole body component 24 homolog antibody
- UniProt
- Q8NBT2
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