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Cathepsin L2 antibody

CTSL2 Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7073348
  • Target See all Cathepsin L2 (CTSL2) Antibodies
    Cathepsin L2 (CTSL2)
    Reactivity
    • 26
    • 12
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 22
    • 4
    Rabbit
    Clonality
    • 23
    • 3
    Polyclonal
    Conjugate
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cathepsin L2 antibody is un-conjugated
    Application
    • 19
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Mouse, Rat
    Purification
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Human Cathepsin V
  • Application Notes
    IHC/IF (H,M,R) 1:1000-1:2000/1:300-1:600
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    Cathepsin L2 (CTSL2)
    Alternative Name
    Cathepsin V (CTSL2 Products)
    Synonyms
    CATL2 antibody, CTSL2 antibody, CTSU antibody, CTSL antibody, CTSL1 antibody, ctsl2 antibody, LOC100232421 antibody, cathepsin V antibody, cathepsin V L homeolog antibody, cathepsin L antibody, CTSV antibody, ctsv.L antibody, ctsv antibody, CTSL antibody, Ctsv antibody
    Background
    Cathepsin V is a lysosomal cysteine protease which has an important role in corneal physiology.Cathepsin V was found to be differentially expressed in relation to pigmentary skin backgrounds, and was about 7.5-folds higher in keratinocytes from lightly pigmented, relative to darkly pigmented skins. It is expressed in primary keratinocytes, melanocytes, and HaCaT keratinocytes, but not in primary fibroblasts. The purified cathepsin L2 was a high molecular weight proteinase of about 78 kDa, but it was unstable to SDS and reducing conditions, which dissociated parts of the proteinase into 66 kDa, 31 kDa and 26 kDa fragments(Food Chemistry,Volume11,Issue4,879-886) and it can form a complex of 70 kDa with an unidentified subunit.
    Gene ID
    1515
    NCBI Accession
    NP_001188504
    UniProt
    O60911
    Pathways
    Toll-Like Receptors Cascades
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