ABCG8 antibody (Internal Region)
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- Target See all ABCG8 Antibodies
- ABCG8 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))
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Binding Specificity
- Internal Region
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ABCG8 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificity
- ABCG8 Antibody detects endogenous levels of total ABCG8.
- Predicted Reactivity
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human ABCG8, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ABCG8 Primary Antibody
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anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8) (AA 1-320) antibody
ABCG8 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8) (AA 176-413) antibodyABCG8 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8) (AA 1-272) antibodyABCG8 Reactivity: Mouse WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8) (N-Term) antibodyABCG8 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8) (AA 1-271) antibodyABCG8 Reactivity: Rat WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8) (AA 566-673) antibodyABCG8 Reactivity: Human, Rat WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8) (C-Term) antibodyABCG8 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- ABCG8 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))
- Alternative Name
- ABCG8 (ABCG8 Products)
- Synonyms
- DDBDRAFT_0167690 antibody, DDBDRAFT_0191232 antibody, DDB_0167690 antibody, DDB_0191232 antibody, zgc:172358 antibody, GBD4 antibody, STSL antibody, 1300003C16Rik antibody, AI114946 antibody, sterolin-2 antibody, ATP binding cassette subfamily G member 8 antibody, ATP-binding cassette sub-family G member 8 antibody, ABC transporter G family protein antibody, ATP-binding cassette, sub-family G (WHITE), member 8 antibody, ABCG8 antibody, PTRG_02054 antibody, abcG8 antibody, abcg8 antibody, Abcg8 antibody
- Background
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Description: ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg2+- and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed:11099417, PubMed:11452359, PubMed:27144356, PubMed:15054092). Required for normal sterol homeostasis (PubMed:11099417, PubMed:11452359, PubMed:15054092). The heterodimer with ABCG5 has ATPase activity (PubMed:16893193, PubMed:20210363, PubMed:27144356).
Gene: ABCG8
- Molecular Weight
- 76kDa
- Gene ID
- 64241
- UniProt
- Q9H221
- Pathways
- Lipid Metabolism
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