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Serotonin Receptor 6 antibody (Internal Region)

HTR6 Reactivity: Human, Rat, Mouse WB, ELISA, ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6256884
  • Target See all Serotonin Receptor 6 (HTR6) Antibodies
    Serotonin Receptor 6 (HTR6)
    Binding Specificity
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 17
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 17
    Rabbit
    Clonality
    • 17
    Polyclonal
    Conjugate
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Serotonin Receptor 6 antibody is un-conjugated
    Application
    • 6
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    5HT6 Receptor Antibody detects endogenous levels of total 5HT6 Receptor.
    Predicted Reactivity
    Pig,Bovine,Horse,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human 5HT6 Receptor, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product HTR6 Primary Antibody
  • Application Notes
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    Serotonin Receptor 6 (HTR6)
    Alternative Name
    HTR6 (HTR6 Products)
    Synonyms
    5-HT6 antibody, 5-HT6R antibody, 5-hydroxytryptamine (serotonin) receptor 6 antibody, 5-hydroxytryptamine receptor 6 antibody, Htr6 antibody, HTR6 antibody
    Background

    Description: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs (By similarity). Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity (By similarity). Is an activator of TOR signaling (PubMed:23027611).

    Gene: HTR6

    Molecular Weight
    47 kDa
    Gene ID
    3362
    UniProt
    P50406
    Pathways
    JAK-STAT Signaling
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