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Aromatase antibody (AA 41-140)

CYP19A1 Reactivity: Human, Rat, Mouse, Cow WB, ELISA, IHC (p), ICC, FACS, IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN674529
  • Target See all Aromatase (CYP19A1) Antibodies
    Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))
    Binding Specificity
    • 15
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 41-140
    Reactivity
    • 84
    • 56
    • 37
    • 29
    • 13
    • 13
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse, Cow
    Host
    • 68
    • 19
    • 1
    Rabbit
    Clonality
    • 72
    • 16
    Polyclonal
    Conjugate
    • 40
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This Aromatase antibody is un-conjugated
    Application
    • 79
    • 20
    • 18
    • 14
    • 12
    • 12
    • 12
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Cow, Human, Mouse, Rat
    Predicted Reactivity
    Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Aromatase
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Gan, Chen, Deng, Yuan, Kang, Qiu, Sun, Han, Hu, Li, Wang: "Establishment of an in vitro culture model of theca cells from hierarchical follicles in ducks." in: Bioscience reports, Vol. 37, Issue 3, (2017) (PubMed).

    Lan, Chen, Jan, Chen, Ho: "Differentiation of human embryonic stem cells into functional ovarian granulosa-like cells." in: The Journal of clinical endocrinology and metabolism, Vol. 98, Issue 9, pp. 3713-23, (2013) (PubMed).

  • Target
    Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))
    Alternative Name
    Aromatase (CYP19A1 Products)
    Synonyms
    ARO antibody, ARO1 antibody, CPV1 antibody, CYAR antibody, CYP19 antibody, CYPXIX antibody, P-450AROM antibody, Aromatase antibody, Cyp19 antibody, Cyp19a antibody, p450arom antibody, P450 arom antibody, aro antibody, cyp19 antibody, cyp19a antibody, p450arom-A antibody, P450AROM antibody, Ar antibody, ArKO antibody, Int-5 antibody, Int5 antibody, CYP19P1 antibody, CYP19A1 antibody, CYP19a1 antibody, P450aromA antibody, ar1 antibody, cypXIX antibody, etID309862.18 antibody, zgc:136541 antibody, AroB antibody, CYP19a2 antibody, P450aromB antibody, cyp19b antibody, zgc:92614 antibody, cyp19a1 antibody, cytochrome P450 family 19 subfamily A member 1 antibody, cytochrome P450, family 19, subfamily a, polypeptide 1 antibody, cytochrome P450 family 19 subfamily A member 1 L homeolog antibody, aromatase antibody, cytochrome P450 aromatase antibody, cytochrome P450, family 19, subfamily A, polypeptide 1 antibody, cytochrome P450 19A1 antibody, cytochrome P450, family 17, subfamily A, polypeptide 1 antibody, cytochrome P450, family 19 antibody, cytochrome P450, family 19, subfamily A, polypeptide 1a antibody, cytochrome P450, family 19, subfamily A, polypeptide 1b antibody, cytochrome P450 19A1-like antibody, CYP19A1 antibody, Cyp19a1 antibody, cyp19a1.L antibody, SAV_2383 antibody, pfcyp19b-tstr antibody, CYP19 antibody, cyp19a1a antibody, cyp19a1b antibody, LOC101174651 antibody
    Background

    Synonyms: ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-45AROM, Aromatase, Cytochrome P-45AROM, Cytochrome P45 19A1, Estrogen synthase, CYP19A1

    Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity, the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. Belongs to the cytochrome P450 family.

    Gene ID
    1588
    UniProt
    P11511
    Pathways
    Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis
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