CD74 antibody
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- Target See all CD74 Antibodies
- CD74 (HLA-DR-gamma (CD74))
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CD74 antibody is un-conjugated
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Application
- Immunofluorescence (IF), Immunohistochemistry (IHC)
- Cross-Reactivity
- Rat
- Purification
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse CD74
- Top Product
- Discover our top product CD74 Primary Antibody
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anti-HLA-DR-gamma (CD74) (AA 1-106) antibody
CD74 Reactivity: Human WB, FACS, ELISA, ICC Host: Mouse Monoclonal 2D1B3 unconjugated
anti-HLA-DR-gamma (CD74) (AA 78-222) antibodyCD74 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-HLA-DR-gamma (CD74) (AA 64-205) antibodyCD74 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-HLA-DR-gamma (CD74) (AA 1-106) antibodyCD74 Reactivity: Human WB, FACS, ELISA Host: Mouse Monoclonal 2D1B11 unconjugated
anti-HLA-DR-gamma (CD74) antibodyCD74 Reactivity: Human WB, FACS, IF, IHC, IP, ICC Host: Mouse Monoclonal PIN-1 unconjugated
anti-HLA-DR-gamma (CD74) antibodyCD74 Reactivity: Human, Mouse, Baboon FACS, IF, IHC, StM Host: Mouse Monoclonal LN-2 unconjugated
anti-HLA-DR-gamma (CD74) (N-Term) antibodyCD74 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-HLA-DR-gamma (CD74) (AA 73-232) antibodyCD74 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-HLA-DR-gamma (CD74) antibodyCD74 Reactivity: Human WB, IHC Host: Rabbit Monoclonal unconjugated
anti-HLA-DR-gamma (CD74) (AA 65-277) antibodyCD74 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- IHC/IF (M,R) 1:1000-1:4000/1:500-1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- CD74 (HLA-DR-gamma (CD74))
- Alternative Name
- CD74 (CD74 Products)
- Synonyms
- DHLAG antibody, HLADG antibody, II antibody, Ia-GAMMA antibody, CLIP antibody, Ii antibody, INVG34 antibody, Iclp-1 antibody, iclp1 antibody, wu:fb11f09 antibody, wu:fb12a01 antibody, wu:fb13d06 antibody, wu:fk94e07 antibody, Iclp-2 antibody, cd74 antibody, iclp2 antibody, zgc:123161 antibody, CD74 molecule antibody, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) antibody, CD74 molecule, major histocompatibility complex, class II invariant chain a antibody, CD74 molecule, major histocompatibility complex, class II invariant chain b antibody, CD74 antibody, Cd74 antibody, cd74a antibody, cd74b antibody
- Background
- CD74, also known as the MHC class II associated invariant chain (Ii), is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is produced in molar excess over MHC class II and some of this is expressed by an unknown pathway on the cell surface independent of or in association with MHC class II molecules. The half life of CD74 on the cell surface is only 3 to 4 min after which it is internalized.
- Gene ID
- 16149
- NCBI Accession
- NP_001036070
- UniProt
- P04441
- Pathways
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
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