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DBN1 antibody (AA 150-281)

DBN1 Reactivity: Human IHC, StM Host: Mouse Monoclonal DBN1-2879 unconjugated
Catalog No. ABIN6939227
  • Target See all DBN1 Antibodies
    DBN1 (Drebrin 1 (DBN1))
    Binding Specificity
    • 15
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 150-281
    Reactivity
    • 36
    • 20
    • 19
    • 1
    • 1
    Human
    Host
    • 28
    • 8
    • 1
    Mouse
    Clonality
    • 28
    • 9
    Monoclonal
    Conjugate
    • 21
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DBN1 antibody is un-conjugated
    Application
    • 35
    • 13
    • 13
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Immunogen
    Recombinant fragment (aa 150-281) of human DBN1 protein (exact sequence is proprietary)
    Clone
    DBN1-2879
    Isotype
    IgG1 kappa
  • Application Notes

    Positive Control: Brain neurons. Also found in the heart, placenta, skeletal muscle, kidney and pancreas.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    DBN1 (Drebrin 1 (DBN1))
    Alternative Name
    DBN1 (DBN1 Products)
    Synonyms
    D0S117E antibody, DBN1 antibody, LOC733967 antibody, drebrin 1 antibody, drebrin 1 S homeolog antibody, DBN1 antibody, Dbn1 antibody, dbn1.S antibody, dbn1 antibody
    Background
    Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2), and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer s disease and Down syndrome.
    Molecular Weight
    120kDa
    Gene ID
    1627
    UniProt
    Q16643
    Pathways
    Maintenance of Protein Location
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