DDB2 antibody (AA 1-315)
(1 reference)-
- Target See all DDB2 Antibodies
- DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))
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Binding Specificity
- AA 1-315
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DDB2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Sequence
- MAPKKRPETQ KTSEIVLRPR NKRSRSPLEL EPEAKKLCAK GSGPSRRCDS DCLWVGLAGP QILPPCRSIV RTLHQHKLGR ASWPSVQQGL QQSFLHTLDS YRILQKAAPF DRRATSLAWH PTHPSTVAVG SKGGDIMLWN FGIKDKPTFI KGIGAGGSIT GLKFNPLNTN QFYASSMEGT TRLQDFKGNI LRVFASSDTI NIWFCSLDVS ASSRMVVTGD NVGNVILLNM DGKELWNLRM HKKKVTHVAL NPCCDWFLAT ASVDQTVKIW DLRQVRGKAS FLYSLPHRHP VNAACFSPDG ARLLTTDQKS EIRVY
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-315 of human DDB2 (NP_000098.1).
- Isotype
- IgG
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anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) antibody
DDB2 Reactivity: Human, Mouse, Rat WB, IF Host: Rabbit Polyclonal unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) (AA 201-300) antibodyDDB2 Reactivity: Mouse, Rat WB, ELISA, IF (cc), IHC (p), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) (AA 166-383) antibodyDDB2 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) (AA 1-427) antibodyDDB2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) antibodyDDB2 Reactivity: Human, Mouse, Rat WB, IHC, IF, IC Host: Rabbit Polyclonal unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) (AA 1-185) antibodyDDB2 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) (C-Term) antibodyDDB2 Reactivity: Human, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) (AA 1-109) antibodyDDB2 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1F11 unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) (AA 212-407) antibodyDDB2 Reactivity: Mouse WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) (C-Term) antibodyDDB2 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid freeze / thaw cycles
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).
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: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).
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- Target
- DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))
- Alternative Name
- DDB2 (DDB2 Products)
- Synonyms
- 2610043A19Rik antibody, si:dkey-45f10.3 antibody, DDBB antibody, UV-DDB2 antibody, damage specific DNA binding protein 2 antibody, damage-specific DNA binding protein 2 antibody, DDB2 antibody, ddb2 antibody, Ddb2 antibody
- Background
- This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.,DDB2,DDBB,UV-DDB2,XPE,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,DDB2
- Molecular Weight
- 17 kDa/26 kDa/40 kDa/47 kDa
- Gene ID
- 1643
- UniProt
- Q92466
- Pathways
- DNA Damage Repair
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