LCK antibody (AA 23-52)
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- Target See all LCK Antibodies
- LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
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Binding Specificity
- AA 23-52
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LCK antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Purification
- Antigen affinity purified
- Immunogen
- A portion of amino acids 23-52 from the human protein was used as the immunogen for this LCK antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product LCK Primary Antibody
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anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-539) antibody
LCK Reactivity: Human WB, ELISA, IP, RNAi Host: Mouse Monoclonal 3F7-F5 unconjugated
anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-240) antibodyLCK Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 22-36) antibodyLCK Reactivity: Human WB, FACS, IP, ICC Host: Mouse Monoclonal LCK-01 unconjugated
anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-539) antibodyLCK Reactivity: Human ELISA, IHC, IF, IP Host: Rabbit Polyclonal unconjugated
anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 23-52), (N-Term) antibodyLCK Reactivity: Human, Mouse WB, IF, FACS, IHC (p) Host: Rabbit Polyclonal RB3088 unconjugated
anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 468-506), (C-Term) antibodyLCK Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 480-509) antibodyLCK Reactivity: Human WB, ELISA, IHC, FACS Host: Rabbit Polyclonal unconjugated
anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 421-509) antibodyLCK Reactivity: Human, Mouse WB, ELISA, FACS Host: Rabbit Polyclonal unconjugated
anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (pTyr393) antibodyLCK Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (pTyr505) antibodyLCK Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Titration of the LCK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the LCK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
- Alternative Name
- LCK (LCK Products)
- Background
- LSK, which belongs to the SRC subfamily of Tyr protein kinases, may participate in antigen-induced T-cell activation. It binds to phosphatidylinositol 3'-kinase (PI3K) from T lymphocytes through its SH3 domain and to the tyrosine phosphorylated form of KHDRBS1/p70 through its SH2 domain. LSK is bound to the cytoplasmic domain of either CD4 or CD8. This protein is involved in leukemias by a chromosomal translocation t(1,7)(p34,q34) which involves LCK and T-cell receptor beta chain (TCRB) genes.
- UniProt
- P06239
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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