SYNPO2 antibody (Internal Region)
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- Target See all SYNPO2 Antibodies
- SYNPO2 (Synaptopodin 2 (SYNPO2))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SYNPO2 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Western Blotting (WB)
- Specificity
- Synaptopodin Antibody detects endogenous levels of total Synaptopodin.
- Predicted Reactivity
- Bovine,Horse
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Synaptopodin, corresponding to a region within the internal amino acids.
- Isotype
- IgG
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anti-Synaptopodin 2 (SYNPO2) (C-Term) antibody
SYNPO2 Reactivity: Human, Mouse, Rat, Horse, Guinea Pig, Rabbit, Cow, Dog WB Host: Rabbit Polyclonal unconjugated
anti-Synaptopodin 2 (SYNPO2) (N-Term) antibodySYNPO2 Reactivity: Human, Mouse WB, EIA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- SYNPO2 (Synaptopodin 2 (SYNPO2))
- Alternative Name
- SYNPO2 (SYNPO2 Products)
- Synonyms
- SYNOP2 antibody, RGD1564779 antibody, 1110069I04Rik antibody, 2310068J10Rik antibody, 9530006G20Rik antibody, AI848603 antibody, Myo antibody, synaptopodin 2 antibody, synaptopodin-2 antibody, SYNPO2 antibody, LOC100484043 antibody, Synpo2 antibody
- Background
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Description: Has an actin-binding and actin-bundling activity. Can induce the formation of F-actin networks in an isoform-specific manner (PubMed:24005909, PubMed:23225103). At the sarcomeric Z lines is proposed to act as adapter protein that links nascent myofibers to the sarcolemma via ZYX and may play a role in early assembly and stabilization of the Z lines. Involved in autophagosome formation. May play a role in chaperone-assisted selective autophagy (CASA) involved in Z lines maintenance in striated muscle under mechanical tension, may link the client-processing CASA chaperone machinery to a membrane-tethering and fusion complex providing autophagosome membranes (By similarity). Involved in regulation of cell migration (PubMed:22915763, PubMed:25883213). May be a tumor suppressor (PubMed:16885336).
Gene: SYNPO2
- Molecular Weight
- 99-115 kDa
- Gene ID
- 171024
- UniProt
- Q9UMS6
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