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AMACR antibody

Name: AMACR antibody
Brand: antibodies-online
SKU: ABIN968957
Price: 554.4 USD
Availability: InStock

AMACR Reactivity: Human, Mouse WB, IHC, ELISA, ICC Host: Mouse Monoclonal 2A10F3 unconjugated

Western blot analysis using AMACR mouse mAb against Jurkat (1) and LNCaP (2) cell lysate.

Confocal immunofluorescence analysis of LNCaP cells using AMACR mouse mAb (green).

Immunohistochemical analysis of paraffin-embedded human normal prostate tissues (left) and prostate adenocarcinoma tissues (right), showing cytoplasmic localization using AMACR mouse mAb with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded human brain cerebellum using AMACR mouse mAb.

IHC

4 images

(2 references)

Catalog No. ABIN968957

Datasheet as PDF

Target See all AMACR Antibodies

AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
Reactivity
110

32

28

3

3

2

1

1

1
Human, Mouse
Host
78

34

2
Mouse
Compatible Secondaries
Clonality
65

49
Monoclonal
Conjugate
63

8

8

5

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
This AMACR antibody is un-conjugated
Application
87

52

43

35

17

16

14

13

7

6

6

5

3

3

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Purification

purified

Immunogen

Purified recombinant fragment of human AMACR expressed in E. coli.

Clone

2A10F3

Isotype

IgG2b

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anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 297-394) antibody
AMACR Reactivity: Human WB, IHC, StM Host: Mouse Monoclonal AMACR-1864 unconjugated

anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 323-351), (C-Term) antibody
AMACR Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB18736 unconjugated

anti-alpha-Methylacyl-CoA Racemase (AMACR) antibody
AMACR Reactivity: Human WB, IHC, StM Host: Mouse Monoclonal AMACR-1723 unconjugated

anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 1-198) antibody
AMACR Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 323-351) antibody
AMACR Reactivity: Human WB, IHC, ELISA, IF, FACS Host: Rabbit Polyclonal unconjugated

anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 312-326) antibody
Verified AMACR Reactivity: Human WB, IHC, ELISA Host: Goat Polyclonal unconjugated

anti-alpha-Methylacyl-CoA Racemase (AMACR) antibody
AMACR Reactivity: Human IHC, StM Host: Rabbit Polyclonal unconjugated

anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 297-394) antibody
AMACR Reactivity: Human IHC, StM Host: Rabbit Monoclonal AMACR-2748R unconjugated Recombinant Antibody

anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 297-394) antibody
AMACR Reactivity: Human IHC, StM Host: Mouse Monoclonal rAMACR-1864 unconjugated Recombinant Antibody

anti-alpha-Methylacyl-CoA Racemase (AMACR) antibody
AMACR Reactivity: Human WB, IHC (f) Host: Rabbit Monoclonal 13H4 unconjugated

Application Notes

ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000

Restrictions

For Research Use only
Format

Liquid

Buffer

Ascitic fluid containing 0.03 % sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C/-20 °C

Storage Comment

4°C, -20°C for long term storage
Chen, Watson, Marengo, Decker, Coleman, Nelson, Sikes: "Gene expression in the LNCaP human prostate cancer progression model: progression associated expression in vitro corresponds to expression changes associated with prostate cancer progression in vivo." in: Cancer letters, Vol. 244, Issue 2, pp. 274-88, (2006) (PubMed).

Epstein, Herawi: "Prostate needle biopsies containing prostatic intraepithelial neoplasia or atypical foci suspicious for carcinoma: implications for patient care." in: The Journal of urology, Vol. 175, Issue 3 Pt 1, pp. 820-34, (2006) (PubMed).
Target

AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

Alternative Name

AMACR (AMACR Products)

Synonyms

AMACR antibody, DKFZp469O1232 antibody, amacr antibody, NCU04099.1 antibody, MGC89832 antibody, AMACRD antibody, CBAS4 antibody, RACE antibody, RM antibody, Macr1 antibody, Da1-8 antibody, Marc1 antibody, alpha-methylacyl-CoA racemase antibody, PROBABLE ALPHA-METHYLACYL-COA RACEMASE MCR (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase) antibody, Alpha-methylacyl-CoA racemase antibody, alpha-methylacyl-CoA racemase L homeolog antibody, AMACR antibody, mcr antibody, BPSL0064 antibody, Maqu_2037 antibody, UREG_03852 antibody, MCYG_01809 antibody, amacr antibody, amacr.L antibody, MGYG_04259 antibody, NCU04099 antibody, Amacr antibody

Background

Description: AMACR (alpha-methylacyl-CoA racemase) has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMACR protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. AMACR can be used as a positive marker for PIN. Defects in AMACR are the cause of congenital bile acid synthesis defect type 4 (CBAS4), also known as cholestasis, intrahepatic, with defective conversion of trihydroxycoprostanic acid to cholic acid or trihydroxycoprostanic acid in bile. Clinical features include neonatal jaundice, intrahepatic cholestasis, bile duct deficiency and absence of cholic acid from bile.
Aliases: RACE

Molecular Weight

42 kDa

Gene ID

23600

HGNC

23600

Pathways

Monocarboxylic Acid Catabolic Process