MAF antibody (C-Term)
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- Target See all MAF Antibodies
- MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MAF antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- C-Maf Antibody detects endogenous levels of total c-Maf.
- Predicted Reactivity
- Pig,Zebrafish,Bovine,Sheep,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human c-Maf, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
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anti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) (AA 304-403) antibody
MAF Reactivity: Human WB, ELISA Host: Mouse Monoclonal 6B8 unconjugated
anti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) (AA 304-403) antibodyMAF Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 6B6 unconjugated
anti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) (N-Term) antibodyMAF Reactivity: Human, Mouse, Rat, Cow, Chicken, Dog, Guinea Pig, Monkey, Xenopus laevis WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) (C-Term) antibodyMAF Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) (AA 341-403) antibodyMAF Reactivity: Human, Mouse ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) (C-Term) antibodyMAF Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) antibodyMAF Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) (N-Term) antibodyMAF Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Dog, Horse, Guinea Pig, Pig, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
anti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) (AA 55-180) antibodyMAF Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) (AA 376-403), (C-Term) antibodyMAF Reactivity: Human WB Host: Rabbit Polyclonal RB18637 unconjugated
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- Application Notes
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
- Alternative Name
- MAF (MAF Products)
- Synonyms
- MAF antibody, DKFZp459D1731 antibody, 2810401A20Rik antibody, A230108G15Rik antibody, AW047063 antibody, c-maf antibody, CCA4 antibody, c-MAF antibody, Maf2 antibody, cMaf antibody, Z-cmaf antibody, c-Maf antibody, fl13d12 antibody, wu:fl13d12 antibody, C-Maf antibody, MAF bZIP transcription factor antibody, v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) antibody, avian musculoaponeurotic fibrosarcoma oncogene homolog antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a) antibody, MAF antibody, Maf antibody, mafa antibody
- Background
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Description: Acts as a transcriptional activator or repressor. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element. Activates transcription of the CD13 proximal promoter in endothelial cells. Represses transcription of the CD13 promoter in early stages of myelopoiesis by affecting the ETS1 and MYB cooperative interaction. Involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. Binds to the sequence 5'-[GT]G[GC]N[GT]NCTCAGNN-3' in the L7 promoter. Binds to the T-MARE (Maf response element) sites of lens-specific alpha- and beta-crystallin gene promoters. Binds element G1 on the glucagon promoter. Binds an AT-rich region adjacent to the TGC motif (atypical Maf response element) in the CD13 proximal promoter in endothelial cells (By similarity). When overexpressed, represses anti-oxidant response element (ARE)-mediated transcription. Involved either as an oncogene or as a tumor suppressor, depending on the cell context. Binds to the ARE sites of detoxifying enzyme gene promoters.
Gene: MAF
- Molecular Weight
- 41 kDa
- Gene ID
- 4094
- UniProt
- O75444
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