CMA1 antibody
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- Target See all CMA1 Antibodies
- CMA1 (Chymase 1, Mast Cell (CMA1))
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CMA1 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Rat
- Purification
- Affinity purification
- Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse Chymase
- Top Product
- Discover our top product CMA1 Primary Antibody
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anti-Chymase 1, Mast Cell (CMA1) (Internal Region) antibody
Verified CMA1 Reactivity: Human WB, ELISA, IHC Host: Goat Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (C-Term) antibodyCMA1 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 22-247) antibodyCMA1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 22-247) antibodyCMA1 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 1-247) antibodyCMA1 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 9-247) antibodyCMA1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 22-197) antibodyCMA1 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 84-118) antibodyCMA1 Reactivity: Human WB Host: Rabbit Polyclonal RB53046 unconjugated
anti-Chymase 1, Mast Cell (CMA1) antibodyCMA1 Reactivity: Human WB, IHC, IHC (p) Host: Mouse Monoclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 81-247) antibodyCMA1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- IHC/IF (M,R) 1:1000-1:2000/1:500-1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- CMA1 (Chymase 1, Mast Cell (CMA1))
- Alternative Name
- Mast Cell Chymase (CMA1 Products)
- Synonyms
- CYH antibody, MCT1 antibody, chymase antibody, MMCP-5 antibody, Mcp-5 antibody, Mcp5 antibody, Mcpt5 antibody, MCP3P antibody, CMA1 antibody, Chymase antibody, chymase 1 antibody, chymase 1, mast cell antibody, chymase-like antibody, CMA1 antibody, Cma1 antibody, LOC100008644 antibody
- Background
- This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases.
- Gene ID
- 17228
- NCBI Accession
- NP_034910
- UniProt
- P21844
- Pathways
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
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