DMRT1 antibody (AA 195-363)
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- Target See all DMRT1 Antibodies
- DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))
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Binding Specificity
- AA 195-363
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DMRT1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human, Mouse
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Doublesex- and mab-3-related transcription factor 1 protein (195-363AA)
- Isotype
- IgG
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anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) (AA 1-373) antibody
DMRT1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1G11 unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) (AA 296-322), (C-Term) antibodyDMRT1 Reactivity: Human WB Host: Rabbit Polyclonal RB38750 unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) (AA 1-373) antibodyDMRT1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) (AA 1-373) antibodyDMRT1 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) antibodyDMRT1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) (N-Term) antibodyDMRT1 Reactivity: Human, Cow, Dog, Pig WB Host: Rabbit Polyclonal unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) (AA 98-128), (N-Term) antibodyDMRT1 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))
- Alternative Name
- DMRT1 (DMRT1 Products)
- Synonyms
- DMT1 antibody, DMRT1 antibody, zgc:136676 antibody, dmrt1 antibody, dmrt1-alpha antibody, dmt1 antibody, dmrt1-beta antibody, xdmrt1 antibody, doublesex and mab-3 related transcription factor 1 antibody, doublesex and mab-3 related transcription factor 1 L homeolog antibody, doublesex and mab-3 related transcription factor 1 S homeolog antibody, DMRT1 antibody, Dmrt1 antibody, dmrt1 antibody, dmrt1.L antibody, dmrt1.S antibody
- Background
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Background: Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and promotes spermatogonial development by activating spermatogonial differentiation genes, such as SOHLH1. Also plays a key role in postnatal sex maintenance by maintaining testis determination and preventing feminization: represses transcription of female promoting genes such as FOXL2 and activates male-specific genes. May act as a tumor suppressor. May also play a minor role in oogenesis (By similarity).
Aliases: CT154 antibody, DM domain expressed in testis 1 antibody, DM domain expressed in testis protein 1 antibody, DM domain gene expressed in testis antibody, DMRT 1 antibody, dmrt1 antibody, DMRT1_HUMAN antibody, DMT 1 antibody, DMT1 antibody, Doublesex and mab 3 related transcription factor 1 antibody, Doublesex- and mab-3-related transcription factor 1 antibody
- UniProt
- Q9Y5R6
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