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MSTN antibody (AA 281-375)

Name: MSTN antibody (AA 281-375)
SKU: ABIN674469
Price: 384.62 USD
Availability: InStock

MSTN Reactivity: Human, Mouse, Rat, Pig WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

Formalin-fixed and paraffin embedded mouse small intestine labeled Anti-GDF8/MSTN Polyclonal Antibody, Unconjugated (ABIN674469) at 1:200, followed by conjugation to the secondary antibody and DAB staining

IHC

Mouse skeletal muscle lysate probed with Anti GDF8/MSTN Polyclonal Antibody, Unconjugated (ABIN674469) at 1:200 overnight at 4 °C.

SDS

Generously provided by Bradley Elliott from University of Westminster as part of the Bioss Discovery Program.

SDS

Formalin-fixed and paraffin embedded rat heart tissue labeled Anti-GDF8/MSTN Polyclonal Antibody, Unconjugated (ABIN674469) at 1:200, followed by conjugation to the secondary antibody and DAB staining

IHC

4 images

(2 references)

Catalog No. ABIN674469

Datasheet as PDF

Target See all MSTN Antibodies

MSTN (Myostatin (MSTN))
Binding Specificity
15

15

14

11

10

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 281-375
Reactivity
75

48

42

17

9

2

2

2

2

1

1

1

1
Human, Mouse, Rat, Pig
Host
87

14

5

4

3

1

1
Rabbit
Compatible Secondaries
Clonality
98

17
Polyclonal
Conjugate
54

21

9

5

2

2

2

2

2

2

2

2

2

2

2

2

2
This MSTN antibody is un-conjugated
Application
96

47

45

25

25

14

12

9

9

6

5

1

1

1
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity

Human, Mouse, Pig, Rat

Predicted Reactivity

Cow,Sheep,Horse,Chicken

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human GDF8

Isotype

IgG

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anti-Myostatin (MSTN) (AA 267-376) antibody
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anti-Myostatin (MSTN) (AA 268-376) antibody
MSTN Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Myostatin (MSTN) (AA 267-375) antibody
MSTN Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated

anti-Myostatin (MSTN) antibody
MSTN Reactivity: Human WB, ELISA Host: Mouse Monoclonal 6H12 unconjugated

Application Notes

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date

12 months
Qian, Tang, Yang, Wang, Cai, Jiang, Li, Jiang, Gao, Ma, Chen, An, Li, Cui: "Targeted mutations in myostatin by zinc-finger nucleases result in double-muscled phenotype in Meishan pigs." in: Scientific reports, Vol. 5, pp. 14435, (2016) (PubMed).
Target

MSTN (Myostatin (MSTN))

Alternative Name

GDF8/MSTN (MSTN Products)

Synonyms

GDF-8 antibody, GDF8 antibody, gdf8 antibody, mstn antibody, zgc:109749 antibody, Gdf8 antibody, NV13143 antibody, MSLHP antibody, Cmpt antibody, myostatin antibody, myostatin b antibody, growth/differentiation factor 8 antibody, MSTN antibody, mstnb antibody, LOC5577632 antibody, BRAFLDRAFT_290840 antibody, Mstn antibody, mstn antibody

Background

Synonyms: GDF8, MSLHP, Growth/differentiation factor 8, GDF-8, Myostatin, MSTN
Background: The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth. Acts specifically as a negative regulator of skeletal muscle growth. [SUBUNIT] Homodimer, [TISSUE SPECIFICITY] Expressed specifically in developing and adult skeletal muscle. Weak expression in adipose tissue. Belongs to the TGF-beta family.

Gene ID

2660

UniProt

O14793