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MYBPC3 antibody (AA 1070-1123)

MYBPC3 Reactivity: Human, Rat, Mouse ELISA, WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5693035
  • Target See all MYBPC3 Antibodies
    MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))
    Binding Specificity
    • 9
    • 9
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1070-1123
    Reactivity
    • 39
    • 37
    • 26
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 54
    • 2
    • 1
    Rabbit
    Clonality
    • 56
    • 1
    Polyclonal
    Conjugate
    • 25
    • 7
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYBPC3 antibody is un-conjugated
    Application
    • 43
    • 27
    • 23
    • 13
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    Brand
    Picoband™
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for MYBPC3 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.
    Immunogen
    E. coli-derived human MYBPC3 recombinant protein (Position: Q1070-H1123).
  • Application Notes

    Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

    Application Details: Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry(Paraffin-embedded Section), 0.5-1 μg/mL
    Direct ELISA, 0.1-0.5 μg/mL

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • Qian, Gong, Yang, Chen, Chen, Xu, Wu, Tang, Gao, Zeng: "Diastolic dysfunction in spontaneous type 2 diabetes rhesus monkeys: a study using echocardiography and magnetic resonance imaging." in: BMC cardiovascular disorders, Vol. 15, pp. 59, (2015) (PubMed).

  • Target
    MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))
    Alternative Name
    MYBPC3 (MYBPC3 Products)
    Synonyms
    MGC114614 antibody, hm:zehn0716 antibody, im:6900815 antibody, zgc:152717 antibody, zgc:158442 antibody, fhc antibody, cmh4 antibody, mybp-c antibody, CMH4 antibody, FHC antibody, MYBP-C antibody, myosin binding protein C, cardiac S homeolog antibody, myosin binding protein C, cardiac antibody, mybpc3.S antibody, MYBPC3 antibody, mybpc3 antibody, Mybpc3 antibody
    Background

    Synonyms: Myosin-binding protein C, cardiac-type, Cardiac MyBP-C, C-protein, cardiac muscle isoform, MYBPC3

    Background: The myosin-binding protein C, cardiac-type is a protein that in humans is encode by the MYBPC3 gene. MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.

    UniProt
    Q14896
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