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DOCK2 antibody (AA 1551-1830)

DOCK2 Reactivity: Human WB, IP, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1679578
  • Target See all DOCK2 Antibodies
    DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))
    Binding Specificity
    • 15
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1551-1830
    Reactivity
    • 33
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 29
    • 2
    • 2
    Rabbit
    Clonality
    • 31
    • 2
    Polyclonal
    Conjugate
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DOCK2 antibody is un-conjugated
    Application
    • 29
    • 13
    • 13
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)
    Sequence
    FTEEYVRDHP EDQDKLTHLK DLIAWQIPFL GAGIKIHEKR VSDNLRPFHD RMEECFKNLK MKVEKEYGVR EMPDFDDRRV GRPRSMLRSY RQMSIISLAS MNSDCSTPSK PTSESFDLEL ASPKTPRVEQ EEPISPGSTL PEVKLRRSKK RTKRSSVVFA DEKAAAESDL KRLSRKHEFM SDTNLSEHAA IPLKASVLSQ MSFASQSMPT IPALALSVAG IPGLDEANTS PRLSQTFLQL SDGDKKTLTR KKVNQFFKTM LASKSAEEGK QIPDSLSTDL
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1551-1830 of human DOCK2 (NP_004937.1).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:1000,IF,1:50 - 1:200,IP,1:50 - 1:100
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))
    Alternative Name
    DOCK2 (DOCK2 Products)
    Synonyms
    AI662014 antibody, AW122239 antibody, CED-5 antibody, Hch antibody, MBC antibody, dedicator of cytokinesis 2 antibody, dedicator of cyto-kinesis 2 antibody, DOCK2 antibody, dock2 antibody, Dock2 antibody
    Background
    The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP.,DOCK2,IMD40,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Stem Cells,Hematopoietic Progenitors,DOCK2
    Molecular Weight
    38 kDa/211 kDa
    Gene ID
    1794
    UniProt
    Q92608
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