Septin 2 antibody (Internal Region)
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- Target See all Septin 2 (SEPT2) Antibodies
- Septin 2 (SEPT2)
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Septin 2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- SEPT2 Antibody detects endogenous levels of total SEPT2.
- Predicted Reactivity
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human SEPT2, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product SEPT2 Primary Antibody
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anti-Septin 2 (SEPT2) (N-Term) antibody
Verified SEPT2 Reactivity: Human WB, ELISA, IHC Host: Goat Polyclonal unconjugated
anti-Septin 2 (SEPT2) (AA 1-361) antibodySEPT2 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-Septin 2 (SEPT2) (AA 1-361) antibodySEPT2 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Septin 2 (SEPT2) (AA 280-309), (C-Term) antibodySEPT2 Reactivity: Human WB Host: Rabbit Polyclonal RB36619 unconjugated
anti-Septin 2 (SEPT2) antibodySEPT2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Septin 2 (SEPT2) antibodySEPT2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Septin 2 (SEPT2) (AA 112-361) antibodySEPT2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Septin 2 (SEPT2) (N-Term) antibodySEPT2 Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog, Pig, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
anti-Septin 2 (SEPT2) (AA 1-371) antibodySEPT2 Reactivity: Human ELISA Host: Mouse Monoclonal 2F8 unconjugated
anti-Septin 2 (SEPT2) antibodySEPT2 Reactivity: Human, Mouse IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- Septin 2 (SEPT2)
- Alternative Name
- SEPT2 (SEPT2 Products)
- Synonyms
- DIFF6 antibody, NEDD5 antibody, Pnutl3 antibody, hNedd5 antibody, AW208991 antibody, Nedd-5 antibody, Nedd5 antibody, mKIAA0158 antibody, Vesp11 antibody, nedd5 antibody, wu:fb52g01 antibody, wu:fb99a01 antibody, Septin-2A antibody, Septin-A antibody, diff6 antibody, pnutl3 antibody, sept2 antibody, septa antibody, xlsepta antibody, SEPT2 antibody, Sep-02 antibody, Septin-2B antibody, hnedd5 antibody, sept2-B antibody, Septin-2 antibody, septin 2 antibody, septin 2 L homeolog antibody, septin 2-like antibody, COG1487; VapC; putative nucleic acid-binding protein; contains PIN domain antibody, septin 2 S homeolog antibody, SEPT2 antibody, Sept2 antibody, sept2 antibody, sept2.L antibody, SEPT2L antibody, sepT2 antibody, sept2.S antibody
- Background
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Description: Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830). Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes: probably acts by regulating the assembly of the tectonic-like complex (also named B9 complex) by localizing TMEM231 protein. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.
Gene: 2-Sep
- Molecular Weight
- 41 kDa
- Gene ID
- 4735
- UniProt
- Q15019
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