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NPC1 antibody (AA 1230-1278)

NPC1 Reactivity: Human, Mouse, Hamster WB, IHC, IF, IP, IEM Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN540364
  • Target See all NPC1 Antibodies
    NPC1 (Niemann-Pick Disease, Type C1 (NPC1))
    Binding Specificity
    • 8
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1230-1278
    Reactivity
    • 45
    • 18
    • 14
    • 1
    Human, Mouse, Hamster
    Host
    • 40
    • 5
    • 2
    Rabbit
    Clonality
    • 34
    • 13
    Polyclonal
    Conjugate
    • 20
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This NPC1 antibody is un-conjugated
    Application
    • 29
    • 28
    • 19
    • 13
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunoelectron Microscopy (IEM)
    Purpose
    Rabbit polyclonal antibody raised against synthetic peptide of NPC1.
    Specificity
    This antibody is specific to NPC1 protein.
    Cross-Reactivity
    Hamster, Human, Mouse
    Immunogen
    A synthetic peptide corresponding to amino acids 1230-1278 at C-terminus of human NPC1.
    Top Product
    Discover our top product NPC1 Primary Antibody
  • Application Notes
    Immunofluorescence (1:250)
    Western Blot (1:1000-1:3000)
    The optimal working dilution should be determined by the end user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In PBS (0.09 % sodium azide)
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for short term. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Burke, Colvin, Myatt, Graf, Schroeder, Woollett: "Transport of maternal cholesterol to the fetus is affected by maternal plasma cholesterol concentrations in the golden Syrian hamster." in: Journal of lipid research, Vol. 50, Issue 6, pp. 1146-55, (2009) (PubMed).

    Millard, Srivastava, Traub, Schaffer, Ory: "Niemann-pick type C1 (NPC1) overexpression alters cellular cholesterol homeostasis." in: The Journal of biological chemistry, Vol. 275, Issue 49, pp. 38445-51, (2001) (PubMed).

    Frolov, Srivastava, Daphna-Iken, Traub, Schaffer, Ory: "Cholesterol overload promotes morphogenesis of a Niemann-Pick C (NPC)-like compartment independent of inhibition of NPC1 or HE1/NPC2 function." in: The Journal of biological chemistry, Vol. 276, Issue 49, pp. 46414-21, (2001) (PubMed).

  • Target
    NPC1 (Niemann-Pick Disease, Type C1 (NPC1))
    Alternative Name
    NPC1 (NPC1 Products)
    Gene ID
    4864
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