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PCSK2 antibody (N-Term)

Name: PCSK2 antibody (N-Term)
SKU: ABIN391908
Price: 429 USD
Availability: InStock

PCSK2 Reactivity: Human, Mouse WB, FACS, IHC (p), IF Host: Rabbit Polyclonal RB18543 unconjugated

Anti-PCSK2 Antibody (N-term) at 1:1000 dilution + TT whole cell lysate Lysates/proteins at 20 μg per lane.

Formalin-fixed and paraffin-embedded human brain tissue reacted with PCSK2 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

IHC (p)

Confocal immunofluorescent analysis of PCSK2 Antibody (N-term) (ABIN391908 and ABIN2841722) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).

Western blot analysis of PCSK2 Antibody (N-term) (ABIN391908 and ABIN2841722) in mouse cerebellum tissue lysates (35 μg/lane).

PCSK2 Antibody (N-term) (ABIN391908 and ABIN2841722) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).

FACS

5 images

Catalog No. ABIN391908

Datasheet as PDF

Target See all PCSK2 Antibodies

PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))
Binding Specificity
15

6

4

2

2

2

2

2

2

1

1

1

1

1
AA 87-116, N-Term
Reactivity
25

24

22

2

2

2

2

2

2

2

1

1

1

1
Human, Mouse
Host
40

4

1
Rabbit
Compatible Secondaries
Clonality
41

4
Polyclonal
Conjugate
24

4

3

3

1

1

1

1

1

1

1

1

1

1

1
This PCSK2 antibody is un-conjugated
Application
37

18

13

13

7

5

4

4

3

2

2

2

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Predicted Reactivity

Pig, Rat

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This PCSK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-116 amino acids from the N-terminal region of human PCSK2.

Clone

RB18543

Isotype

Ig Fraction
anti-Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) (AA 87-116) antibody
PCSK2 Reactivity: Human, Mouse WB, ELISA, IHC, FACS, IF Host: Rabbit Polyclonal unconjugated

anti-Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) (AA 318-346) antibody
PCSK2 Reactivity: Human WB, ELISA, IHC, FACS Host: Rabbit Polyclonal unconjugated

anti-Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) (AA 267-391) antibody
PCSK2 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) (AA 318-346) antibody
PCSK2 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB18544 unconjugated

anti-Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) (AA 1-638) antibody
PCSK2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated

anti-Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) (AA 501-609) antibody
PCSK2 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3H4 unconjugated

anti-Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) (AA 351-400) antibody
PCSK2 Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse, Rabbit, Monkey, Chicken, Pig, Bat, Xenopus laevis WB Host: Rabbit Polyclonal unconjugated

anti-Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) antibody
PCSK2 Reactivity: Human, Mouse WB, IHC, FACS, IF/ICC Host: Rabbit Polyclonal unconjugated

anti-Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) (AA 109-637) antibody
PCSK2 Reactivity: Rat WB, ELISA Host: Rabbit Polyclonal unconjugated

anti-Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) (AA 201-300) antibody
PCSK2 Reactivity: Mouse, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Host: Rabbit Polyclonal unconjugated

Application Notes

IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date

6 months
Target

PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))

Alternative Name

PCSK2 (PCSK2 Products)

Synonyms

NEC 2 antibody, NEC-2 antibody, NEC2 antibody, PC2 antibody, SPC2 antibody, PCSK2 antibody, 6330411F23Rik antibody, AI839700 antibody, Nec-2 antibody, Nec2 antibody, Phpp-2 antibody, pc2 antibody, nec2 antibody, spc2 antibody, pcsk2 antibody, pcsk2-A antibody, proprotein convertase subtilisin/kexin type 2 antibody, proprotein convertase subtilisin/kexin type 2 L homeolog antibody, PCSK2 antibody, pcsk2 antibody, Pcsk2 antibody, pcsk2.L antibody

Background

PCSK2 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This protein is a proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. The protein is also known to cleave proopiomelanocortin, proenkephalin, prodynorphin and proluteinizing-hormone-releasing hormone.

Molecular Weight

70565

Gene ID

5126

NCBI Accession

NP_001188457, NP_001188458, NP_002585

UniProt

P16519

Pathways

Peptide Hormone Metabolism, cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity