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E2F5 antibody (N-Term)

E2F5 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB23726 unconjugated
Catalog No. ABIN652951
  • Target See all E2F5 Antibodies
    E2F5
    Binding Specificity
    • 7
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 66-93, N-Term
    Reactivity
    • 39
    • 14
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 37
    • 2
    Rabbit
    Clonality
    • 37
    • 2
    Polyclonal
    Conjugate
    • 17
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This E2F5 antibody is un-conjugated
    Application
    • 29
    • 22
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    M, X, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This E2F5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-93 amino acids from the N-terminal region of human E2F5.
    Clone
    RB23726
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:2000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Song, Gong, Yan, Hong, Wang, Wu, Li, Li, Cao: "Sj7170, a unique dual-function peptide with a specific ?-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom." in: The Journal of biological chemistry, Vol. 289, Issue 17, pp. 11667-80, (2014) (PubMed).

  • Target
    E2F5
    Alternative Name
    E2F5 (E2F5 Products)
    Synonyms
    AU024671 antibody, E2F-5 antibody, E2f-5 antibody, E2F4 antibody, cb735 antibody, zgc:111879 antibody, E2F transcription factor 5 antibody, E2f5 antibody, e2f5 antibody, E2F5 antibody
    Background
    E2F5 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB.
    Molecular Weight
    37610
    Gene ID
    1875
    NCBI Accession
    NP_001077057, NP_001077058, NP_001942
    UniProt
    Q15329
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