For best experience we recommend to activate Javascript in your browser.

ECT2 antibody (AA 283-453)

Name: ECT2 antibody (AA 283-453)
Brand: antibodies-online
SKU: ABIN7165313
Price: 328.9 USD
Availability: InStock

ECT2 Reactivity: Human WB, ELISA, IHC, IP Host: Rabbit Polyclonal unconjugated

Western Blot Positive WB detected in: Hela whole cell lysate, A549 whole cell lysate, 293T whole cell lysate All lanes:ECT2 antibody at 2.

IHC image of ABIN7165313 diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system.

IHC

Immunoprecipitating ECT2 in Hela whole cell lysate Lane 1: Rabbit control IgG instead of ABIN7165313 in Hela whole cell lysate.

3 images

Catalog No. ABIN7165313

Datasheet as PDF

Target See all ECT2 Antibodies

ECT2 (Epithelial Cell Transforming Sequence 2 Oncogene (ECT2))
Binding Specificity
15

7

7

6

6

4

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 283-453
Reactivity
61

12

4

3

3

3

2

2

2

1

1
Human
Host
56

4

1
Rabbit
Compatible Secondaries
Clonality
57

4
Polyclonal
Conjugate
22

8

6

4

2

2

2

2

2

2

2

2

1

1

1

1

1
This ECT2 antibody is un-conjugated
Application
46

23

18

14

14

8

4

2

2

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Cross-Reactivity

Human

Purification

>95%, Protein G purified

Immunogen

Recombinant Human Protein ECT2 protein (283-453AA)

Isotype

IgG
anti-Epithelial Cell Transforming Sequence 2 Oncogene (ECT2) (N-Term) antibody
Verified ECT2 Reactivity: Human ELISA, IF, FACS Host: Goat Polyclonal unconjugated

anti-Epithelial Cell Transforming Sequence 2 Oncogene (ECT2) (AA 453-647) antibody
ECT2 Reactivity: Human WB, IHC, ICC Host: Rabbit Polyclonal unconjugated

anti-Epithelial Cell Transforming Sequence 2 Oncogene (ECT2) (AA 166-348) antibody
ECT2 Reactivity: Human WB, IHC, ICC Host: Rabbit Polyclonal unconjugated

anti-Epithelial Cell Transforming Sequence 2 Oncogene (ECT2) (AA 781-883) antibody
ECT2 Reactivity: Human, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Epithelial Cell Transforming Sequence 2 Oncogene (ECT2) (AA 46-145) antibody
ECT2 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 5D4 unconjugated

anti-Epithelial Cell Transforming Sequence 2 Oncogene (ECT2) (AA 200-460) antibody
ECT2 Reactivity: Human WB Host: Mouse Monoclonal 1691CT516-3-3 unconjugated

anti-Epithelial Cell Transforming Sequence 2 Oncogene (ECT2) antibody
ECT2 Reactivity: Human, Mouse ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-Epithelial Cell Transforming Sequence 2 Oncogene (ECT2) (AA 785-795), (pThr790) antibody
ECT2 Reactivity: Human WB, ELISA, IP Host: Rabbit Polyclonal unconjugated

anti-Epithelial Cell Transforming Sequence 2 Oncogene (ECT2) (N-Term) antibody
ECT2 Reactivity: Human IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Epithelial Cell Transforming Sequence 2 Oncogene (ECT2) (AA 580-629) antibody
ECT2 Reactivity: Human, Mouse, Rat, Dog, Monkey, Guinea Pig, Rabbit, Horse, Bat WB Host: Rabbit Polyclonal unconjugated

Application Notes

Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IP:1:200-1:2000,

Restrictions

For Research Use only
Format

Liquid

Buffer

Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

-20 °C,-80 °C

Storage Comment

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target

ECT2 (Epithelial Cell Transforming Sequence 2 Oncogene (ECT2))

Alternative Name

ECT2 (ECT2 Products)

Synonyms

ECT2 antibody, arhgef31 antibody, xect2 antibody, AI528536 antibody, mKIAA4037 antibody, ARHGEF31 antibody, ect2 antibody, epithelial cell transforming 2 antibody, ect2 oncogene antibody, epithelial cell transforming 2 S homeolog antibody, ECT2 antibody, ect2 antibody, Ect2 antibody, ect2.S antibody

Background

Background: Guanine nucleotide exchange factor (GEF) that catalyzes the exchange of GDP for GTP. Promotes guanine nucleotide exchange on the Rho family members of small GTPases, like RHOA, RHOC, RAC1 and CDC42. Required for signal transduction pathways involved in the regulation of cytokinesis. Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Regulates the translocation of RHOA from the central spindle to the equatorial region. Plays a role in the control of mitotic spindle assembly, regulates the activation of CDC42 in metaphase for the process of spindle fibers attachment to kinetochores before chromosome congression. Involved in the regulation of epithelial cell polarity, participates in the formation of epithelial tight junctions in a polarity complex PARD3-PARD6-protein kinase PRKCQ-dependent manner. Plays a role in the regulation of neurite outgrowth. Inhibits phenobarbital (PB)-induced NR1I3 nuclear translocation. Stimulates the activity of RAC1 through its association with the oncogenic PARD6A-PRKCI complex in cancer cells, thereby acting to coordinately drive tumor cell proliferation and invasion. Also stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.
Aliases: ECT2Protein ECT2 antibody, Epithelial cell-transforming sequence 2 oncogene antibody

UniProt

Q9H8V3

Pathways

Neurotrophin Signaling Pathway, Cell-Cell Junction Organization