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EEF1A2 antibody

KO Validated EEF1A2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855358
  • Target See all EEF1A2 Antibodies
    EEF1A2 (Eukaryotic Translation Elongation Factor 1 alpha 2 (EEF1A2))
    Reactivity
    • 37
    • 28
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 47
    • 1
    • 1
    Rabbit
    Clonality
    • 48
    • 1
    Polyclonal
    Conjugate
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This EEF1A2 antibody is un-conjugated
    Application
    • 42
    • 21
    • 17
    • 13
    • 13
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    Based on a BLAST result, it may also cross with human EEF1A1.
    Cross-Reactivity
    Human, Mouse, Rat, Zebrafish (Danio rerio)
    Characteristics
    Rabbit Polyclonal antibody to EEF1A2 (eukaryotic translation elongation factor 1 alpha 2)
    EEF1A2 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Grade
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human EEF1A2. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: Mouse brain , mouse muscle , rat brain , 293T

    Validation: KO/KD

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.21 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Losada, Muñoz-Alonso, García, Sánchez-Murcia, Martínez-Leal, Domínguez, Lillo, Gago, Galmarini: "Translation Elongation Factor eEF1A2 is a Novel Anticancer Target for the Marine Natural Product Plitidepsin." in: Scientific reports, Vol. 6, pp. 35100, (2018) (PubMed).

  • Target
    EEF1A2 (Eukaryotic Translation Elongation Factor 1 alpha 2 (EEF1A2))
    Alternative Name
    eukaryotic translation elongation factor 1 alpha 2 (EEF1A2 Products)
    Synonyms
    EEF1AL antibody, EF-1-alpha-2 antibody, EF1A antibody, HS1 antibody, STN antibody, STNL antibody, EEF1A2 antibody, Eef1a antibody, S1 antibody, wasted antibody, wst antibody, Ps10 antibody, RATPS10 antibody, Stnl antibody, eef1al antibody, ef1a antibody, stnl antibody, EEF1A-2 antibody, zgc:92085 antibody, eukaryotic translation elongation factor 1 alpha 2 antibody, eukaryotic translation elongation factor 1 alpha 1 antibody, eukaryotic translation elongation factor 1 alpha 2 S homeolog antibody, putative elongation factor 1-alpha-like 3 antibody, EEF1A2 antibody, EEF1A1 antibody, Eef1a2 antibody, eef1a2.S antibody, eef1a2 antibody, LOC739210 antibody, EEF1 antibody, eef1 antibody
    Background
    This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Nucleus
    Molecular Weight
    50 kDa
    Gene ID
    1917
    UniProt
    Q05639
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