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Filamin A antibody (pSer2152)

FLNA Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6256196
  • Target See all Filamin A (FLNA) Antibodies
    Filamin A (FLNA) (Filamin A, alpha (FLNA))
    Binding Specificity
    • 15
    • 15
    • 12
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer2152
    Reactivity
    • 102
    • 32
    • 27
    • 3
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 95
    • 6
    • 1
    Rabbit
    Clonality
    • 85
    • 17
    Polyclonal
    Conjugate
    • 43
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This Filamin A antibody is un-conjugated
    Application
    • 51
    • 30
    • 28
    • 28
    • 27
    • 23
    • 11
    • 9
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Phospho-Filamin A (Ser2152) Antibody detects endogenous levels of Filamin A only when phosphorylated at Serine 2152.
    Predicted Reactivity
    Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogen
    A synthesized peptide derived from human Filamin A around the phosphorylation site of Ser2152.
    Isotype
    IgG
    Top Product
    Discover our top product FLNA Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:100-1:500, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    Filamin A (FLNA) (Filamin A, alpha (FLNA))
    Alternative Name
    FLNA (FLNA Products)
    Synonyms
    ABP-280 antibody, ABPX antibody, CSBS antibody, CVD1 antibody, FLN antibody, FLN-A antibody, FLN1 antibody, FMD antibody, MNS antibody, NHBP antibody, OPD antibody, OPD1 antibody, OPD2 antibody, XLVD antibody, XMVD antibody, fb98b06 antibody, wu:fb98b06 antibody, wu:fd09g03 antibody, wu:fd49a06 antibody, Dilp2 antibody, F730004A14Rik antibody, Fln1 antibody, filamin-1 antibody, RGD1560614 antibody, MGC147094 antibody, CG3937 antibody, Cher antibody, Dmel\\CG3937 antibody, Fil antibody, joy antibody, sko antibody, filamin A antibody, filamin A, alpha (actin binding protein 280) antibody, filamin, alpha antibody, filamin-A antibody, cheerio antibody, FLNA antibody, flna antibody, Flna antibody, LOC587317 antibody, cher antibody, LOC100380643 antibody
    Background

    Description: Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance (By similarity).

    Gene: FLNA

    Molecular Weight
    280kDa
    Gene ID
    2316
    UniProt
    P21333
    Pathways
    TCR Signaling, Maintenance of Protein Location
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