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RAB17 antibody (Internal Region)

RAB17 Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6264559
  • Target See all RAB17 Antibodies
    RAB17 (RAB17, Member RAS Oncogene Family (RAB17))
    Binding Specificity
    • 15
    • 7
    • 7
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 33
    • 26
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 43
    • 3
    • 1
    Rabbit
    Clonality
    • 44
    • 3
    Polyclonal
    Conjugate
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This RAB17 antibody is un-conjugated
    Application
    • 40
    • 22
    • 13
    • 13
    • 6
    • 5
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    RAB17 Antibody detects endogenous levels of total RAB17.
    Predicted Reactivity
    Pig,Bovine,Sheep,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human RAB17, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product RAB17 Primary Antibody
  • Application Notes
    WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    RAB17 (RAB17, Member RAS Oncogene Family (RAB17))
    Alternative Name
    RAB17 (RAB17 Products)
    Synonyms
    RAB17 antibody, AW413472 antibody, RGD1562478 antibody, rab17 antibody, RAB17, member RAS oncogene family antibody, EDI_278050 antibody, EDI_260720 antibody, EDI_050010 antibody, RAB17 antibody, Rab17 antibody
    Background

    Description: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in transcytosis, the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. Mainly observed in epithelial cells, transcytosis mediates for instance, the transcellular transport of immunoglobulins from the basolateral surface to the apical surface. Most probably controls membrane trafficking through apical recycling endosomes in a post-endocytic step of transcytosis. Required for melanosome transport and release from melanocytes, it also regulates dendrite and dendritic spine development (By similarity). May also play a role in cell migration.

    Gene: RAB17

    Molecular Weight
    23 kDa
    Gene ID
    64284
    UniProt
    Q9H0T7
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