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TRPV5 antibody (N-Term)

TRPV5 Reactivity: Human, Rat, Mouse, Cow, Dog, Pig, Rabbit, Guinea Pig, Horse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2783755
  • Target See all TRPV5 Antibodies
    TRPV5 (Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5))
    Binding Specificity
    • 11
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Rat, Mouse, Cow, Dog, Pig, Rabbit, Guinea Pig, Horse
    Host
    • 33
    • 4
    • 2
    • 1
    Rabbit
    Clonality
    • 37
    • 3
    Polyclonal
    Conjugate
    • 22
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRPV5 antibody is un-conjugated
    Application
    • 29
    • 24
    • 6
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    MLQQKRILES PLLRASKEND LSVLRQLLLD CTCDVRQRGA LGETALHIAA
    Predicted Reactivity
    Cow: 85%, Dog: 85%, Guinea Pig: 85%, Horse: 77%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 77%, Rat: 85%
    Characteristics
    This is a rabbit polyclonal antibody against TRPV5. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human TRPV5
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 729 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Cha, Wu, Huang: "Protein kinase C inhibits caveolae-mediated endocytosis of TRPV5." in: American journal of physiology. Renal physiology, Vol. 294, Issue 5, pp. F1212-21, (2008) (PubMed).

  • Target
    TRPV5 (Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5))
    Alternative Name
    TRPV5 (TRPV5 Products)
    Synonyms
    CaT2 antibody, Ecac1 antibody, CAT2 antibody, ECAC1 antibody, OTRPC3 antibody, D630033B11 antibody, TRPV5 antibody, ECAC antibody, cat2 antibody, xcat2 antibody, transient receptor potential cation channel, subfamily V, member 5 antibody, transient receptor potential cation channel subfamily V member 5 antibody, calcium transporter 2 L homeolog antibody, Trpv5 antibody, TRPV5 antibody, LOC100011049 antibody, trpv5 antibody, cat2.L antibody
    Background
    TRPV5 is a member of the transient receptor family and the TrpV subfamily. TRPV5, a calcium-selective channel, has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. TRPV5 forms homotetramers or heterotetramers and is activated by a low internal calcium level.This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2486 AF304464.1 86-2571
    Alias Symbols: CAT2, ECAC1, OTRPC3
    Protein Interaction Partner: EWSR1, CALB1, S100A10, ANXA2,
    Protein Size: 729
    Molecular Weight
    82 kDa
    Gene ID
    56302
    NCBI Accession
    NM_019841, NP_062815
    UniProt
    Q9NQA5
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