Ensa antibody
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- Target See all Ensa (ENSA) Antibodies
- Ensa (ENSA) (Endosulfine alpha (ENSA))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Ensa antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
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Rabbit Polyclonal antibody to ENSA (endosulfine alpha)
ENSA antibody - Purification
- Purified by antigen-affinity chromatography.
- Grade
- KO Validated
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human ENSA. The exact sequence is proprietary.
- Isotype
- IgG
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anti-Endosulfine alpha (ENSA) (AA 39-66) antibody
ENSA Reactivity: Human, Mouse WB, FACS Host: Rabbit Polyclonal RB19622 unconjugated
anti-Endosulfine alpha (ENSA) (AA 1-121) antibodyENSA Reactivity: Human ELISA, WB Host: Mouse Monoclonal 1H7 unconjugated
anti-Endosulfine alpha (ENSA) (AA 1-121) antibodyENSA Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Endosulfine alpha (ENSA) antibodyENSA Reactivity: Human, Mouse, Rat ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Endosulfine alpha (ENSA) (AA 1-121) antibodyENSA Reactivity: Human ELISA, WB Host: Mouse Monoclonal 1E8 unconjugated
anti-Endosulfine alpha (ENSA) (AA 1-121) antibodyENSA Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Endosulfine alpha (ENSA) (AA 46-74), (Middle Region) antibodyENSA Reactivity: Human, Mouse WB, FACS, EIA Host: Rabbit Polyclonal unconjugated
anti-Endosulfine alpha (ENSA) (AA 1-100) antibodyENSA Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Endosulfine alpha (ENSA) (N-Term) antibodyENSA Reactivity: Human, Mouse, Rat, Pig, Rabbit, Cow, Dog, Horse WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: 293T
Validation: KO/KD
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.6 mg/mL
- Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- Ensa (ENSA) (Endosulfine alpha (ENSA))
- Alternative Name
- endosulfine alpha (ENSA Products)
- Synonyms
- ARPP-19e antibody, 1700020C18Rik antibody, 2610007F17Rik antibody, AI451924 antibody, ensa antibody, si:dkeyp-24a7.3 antibody, ensaa antibody, endosulfine alpha antibody, endosulfine alpha a antibody, endosulfine alpha S homeolog antibody, ENSA antibody, Ensa antibody, ensa antibody, ensaa antibody, ensa.S antibody
- Background
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The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.
Cellular Localization: Cytoplasm - Molecular Weight
- 13 kDa
- Gene ID
- 2029
- UniProt
- O43768
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