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SLC29A1 antibody (C-Term)

SLC29A1 Reactivity: Human, Mouse WB, IHC (p), FACS Host: Rabbit Polyclonal RB09157 unconjugated
Catalog No. ABIN387940
  • Target See all SLC29A1 Antibodies
    SLC29A1 (Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1))
    Binding Specificity
    • 15
    • 9
    • 8
    • 8
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 402-431, C-Term
    Reactivity
    • 86
    • 21
    • 18
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 86
    • 2
    • 1
    Rabbit
    Clonality
    • 88
    Polyclonal
    Conjugate
    • 38
    • 9
    • 8
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC29A1 antibody is un-conjugated
    Application
    • 51
    • 45
    • 19
    • 13
    • 13
    • 11
    • 7
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Predicted Reactivity
    Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This ENT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 402-431 amino acids from the C-terminal region of human ENT1.
    Clone
    RB09157
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P-Leica: 1:500. FC: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Grenz, Bauerle, Dalton, Ridyard, Badulak, Tak, McNamee, Clambey, Moldovan, Reyes, Klawitter, Ambler, Magee, Christians, Brodsky, Ravid, Choi, Wen, Lukashev, Blackburn, Osswald, Coe, Nürnberg, Haase et al.: "Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice. ..." in: The Journal of clinical investigation, Vol. 122, Issue 2, pp. 693-710, (2012) (PubMed).

    Ibarra, Jain, Pfeiffer: "Host-based ribavirin resistance influences hepatitis C virus replication and treatment response." in: Journal of virology, Vol. 85, Issue 14, pp. 7273-83, (2011) (PubMed).

    Ibarra, Pfeiffer: "Reduced ribavirin antiviral efficacy via nucleoside transporter-mediated drug resistance." in: Journal of virology, Vol. 83, Issue 9, pp. 4538-47, (2009) (PubMed).

  • Target
    SLC29A1 (Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1))
    Alternative Name
    ENT1 (SLC29A1 Products)
    Synonyms
    ENT1 antibody, rENT1 antibody, 1200014D21Rik antibody, AA407560 antibody, solute carrier family 29 member 1 (Augustine blood group) antibody, solute carrier family 29 member 1 antibody, solute carrier family 29 (nucleoside transporters), member 1 antibody, SLC29A1 antibody, Slc29a1 antibody
    Background
    ENT1 is a member of the equilibrative nucleoside transporter family. It is a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies.
    Molecular Weight
    50219
    Gene ID
    2030
    NCBI Accession
    NP_001071642, NP_001071643, NP_001071644, NP_001071645, NP_004946
    UniProt
    Q99808
    Pathways
    Carbohydrate Homeostasis, Synaptic Membrane
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