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EPHA1 antibody (AA 296-414)

EPHA1 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7151827
  • Target See all EPHA1 Antibodies
    EPHA1 (Ephrin Type A Receptor 1 (EPHA1))
    Binding Specificity
    • 15
    • 9
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 296-414
    Reactivity
    • 96
    • 51
    • 9
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Host
    • 105
    • 8
    Rabbit
    Clonality
    • 106
    • 8
    Polyclonal
    Conjugate
    • 49
    • 11
    • 10
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    This EPHA1 antibody is un-conjugated
    Application
    • 67
    • 53
    • 29
    • 13
    • 13
    • 13
    • 12
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human, Mouse
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Ephrin type-A receptor 1 protein (296-414AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    EPHA1 (Ephrin Type A Receptor 1 (EPHA1))
    Alternative Name
    EPHA1 (EPHA1 Products)
    Synonyms
    EPH antibody, EPHT antibody, EPHT1 antibody, 5730453L17Rik antibody, AL033318 antibody, Eph antibody, Esk antibody, EPHA9 antibody, EPH receptor A1 antibody, Eph receptor A1 antibody, EPHA1 antibody, Epha1 antibody
    Background

    Background: Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. Plays also a role in angiogenesis and regulates cell proliferation. May play a role in apoptosis.

    Aliases: EPH antibody, EPH receptor A1 antibody, EPH tyrosine kinase 1 antibody, EPH tyrosine kinase antibody, Epha1 antibody, EPHA1_HUMAN antibody, Ephrin receptor Eph A1 antibody, Ephrin type A receptor 1 antibody, Ephrin type-A receptor 1 antibody, EPHT 1 antibody, EPHT antibody, EPHT1 antibody, Erythropoietin producing hepatoma amplified sequence antibody, Erythropoietin-producing hepatoma receptor antibody, Esk antibody, hEpha1 antibody, MGC163163 antibody, Oncogene EPH antibody, Soluble EPHA1 variant 1 antibody, Soluble EPHA1 variant 2 antibody, Tyrosine protein kinase receptor EPH antibody, Tyrosine-protein kinase receptor EPH antibody

    UniProt
    P21709
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