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EPH Receptor A7 antibody (AA 181-280)

Name: EPH Receptor A7 antibody (AA 181-280)
SKU: ABIN722005
Price: 384.62 USD
Availability: InStock

EPHA7 Reactivity: Human, Mouse, Rat WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

Formalin-fixed and paraffin embedded mouse embryo labeled with Rabbit Anti EphA7/Eph receptor A7 Polyclonal Antibody, Unconjugated (ABIN722005) at 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC

Formalin-fixed and paraffin embedded mouse embryo labeled with Rabbit Anti EphA7/Eph receptor A7 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC (p)

Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti EphA7/Eph receptor A7 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC (p)

Mouse spleen cells probed with Rabbit Anti-Eph receptor A7 Polyclonal Antibody .

FACS

Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti EphA7/Eph receptor A7 Polyclonal Antibody, Unconjugated (ABIN722005) at 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC

Formalin-fixed and paraffin-embedded rat testis labeled with Anti--EphA7/Eph receptor A7 Polyclonal Antibody, Unconjugated (ABIN722005) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C.

6 images

Catalog No. ABIN722005

Datasheet as PDF

Target See all EPH Receptor A7 (EPHA7) Antibodies

EPH Receptor A7 (EPHA7)
Binding Specificity
15

10

9

9

8

8

7

6

4

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 181-280
Reactivity
90

41

41

6

6

5

2

2

2

1

1

1
Human, Mouse, Rat
Host
87

3

1
Rabbit
Compatible Secondaries
Clonality
88

3
Polyclonal
Conjugate
30

9

7

5

4

4

4

4

4

4

4

3

1

1

1

1

1

1

1

1

1
This EPH Receptor A7 antibody is un-conjugated
Application
57

38

25

24

12

12

7

4

2

2

2

1

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity

There is a chance that this protein will cross-react with EphA4 based on a 73 % non-sequential sequence similarity.

Cross-Reactivity

Human, Mouse, Rat

Predicted Reactivity

Dog,Cow,Horse,Chicken,Rabbit

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human EphA7

Isotype

IgG
anti-EPH Receptor A7 (EPHA7) (AA 896-925), (C-Term) antibody
EPHA7 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB1641-RB1642 unconjugated

anti-EPH Receptor A7 (EPHA7) (AA 11-41), (N-Term) antibody
EPHA7 Reactivity: Human FACS, IHC (p) Host: Rabbit Polyclonal RB1639 unconjugated

anti-EPH Receptor A7 (EPHA7) (AA 27-210) antibody
EPHA7 Reactivity: Human WB, ELISA, IHC Host: Mouse Monoclonal 6C8G7 unconjugated

anti-EPH Receptor A7 (EPHA7) (AA 28-182) antibody
EPHA7 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-EPH Receptor A7 (EPHA7) (AA 1-279) antibody
EPHA7 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1G11 unconjugated

anti-EPH Receptor A7 (EPHA7) (Ser347) antibody
EPHA7 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated

anti-EPH Receptor A7 (EPHA7) (Internal Region) antibody
EPHA7 Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-EPH Receptor A7 (EPHA7) (pTyr791) antibody
EPHA7 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated

anti-EPH Receptor A7 (EPHA7) (pTyr791) antibody
EPHA7 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated

anti-EPH Receptor A7 (EPHA7) (C-Term) antibody
EPHA7 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated

Application Notes

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date

12 months
Target

EPH Receptor A7 (EPHA7)

Alternative Name

EphA7 (EPHA7 Products)

Background

Synonyms: EHK3, EK11, EHK-3, HEK11, Ephrin type-A receptor 7, EPH homology kinase 3, EPH-like kinase 11, EPHA7
Background: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus. May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity. Forward signaling may result in activation of components of the ERK signaling pathway including MAP2K1, MAP2K2, MAPK1 AND MAPK3 which are phosphorylated upon activation of EPHA7.

Gene ID

2045

UniProt

Q15375

Pathways

RTK Signaling